|
Successful management of hypoadrenocorticism in a French Bulldog by a smaller dose and lesser frequency of the desoxycorticosterone pivalate: a case report |
|---|---|
| รหัสดีโอไอ | |
| Creator | Walasinee Sakcamduang |
| Title | Successful management of hypoadrenocorticism in a French Bulldog by a smaller dose and lesser frequency of the desoxycorticosterone pivalate: a case report |
| Contributor | Phuttipan Channgam |
| Publisher | Chulalongkorn University |
| Publication Year | 2564 |
| Journal Title | The Thai Journal of Veterinary Medicine |
| Journal Vol. | 51 |
| Journal No. | 1 |
| Page no. | 197 |
| Keyword | Addison's disease, cortisol, desoxycorticosterone pivalate, dog, hypoadrenocorticism |
| URL Website | https://he01.tci-thaijo.org/index.php/tjvm/index |
| Website title | https://he01.tci-thaijo.org/index.php/tjvm/index |
| ISSN | 0125-6491 |
| Abstract | A 1 year and 4 months old, intact female French Bulldog was presented because of weakness, anorexia, and vomiting for 3 days. Laboratory findings included azotemia, hyponatremia, hypochloremia, sodium to potassium (Na:K) ratio was 23.88, and the lowerlevel of basal cortisol concentration than the detection limit.The small size of both adrenal glandsobtained from abdominal ultrasonography. Subsequently, the adrenocorticotropic hormone (ACTH) stimulation test was performed, and the diagnosis of hypoadrenocorticismwas confirmed.The desoxycorticosterone pivalate (DOCP)with asmaller dose and lesser frequency than the recommendationof 2.2 mg/kg every 25 days. The dog received DOCP subcutaneous injection at a dose of 1.5 mg/kg initially and followed by 1.37 mg/kg 55 days after the first injection,1.37 mg/kg 28 days after the second injection, and more than 84 days after a dose of 1.37 mg/kg of the third injection. Glucocorticoid administrations were in recommended doses for the whole period of management.Improvement ofclinical manifestationsand laboratory parameters of the dog was observed a week later after the DOCP intervention. A smaller than recommended dose and lesserfrequency of the DOCP with prednisolone seems adequate for controlling clinical problems in the successful management of the hypoadrenocorticism in a French Bulldog. |
