Twin Pregnancy Presenting with Hydatidiform Mole and Co-existing Living Fetus with Ovarian Venous Thrombosis: A case report
รหัสดีโอไอ
Creator Karit Jayasakoon
Title Twin Pregnancy Presenting with Hydatidiform Mole and Co-existing Living Fetus with Ovarian Venous Thrombosis: A case report
Contributor Densak Pongrojpaw, Awassada Punyashthira, Araya Sammor, Athita Chanthasenanont, Komsun Suwannarurk
Publisher PIMDEE Co., Ltd.
Publication Year 2567
Journal Title Thai Journal of Obstetrics and Gynaecology
Journal Vol. 32
Journal No. 4
Page no. 320-327
Keyword molar pregnancy, trophoblastic disease, co-existing normal fetus, venous occlusion
URL Website https://tci-thaijo.org/index.php/tjog/index
Website title www.tci-thaijo.org
ISSN 2673-0871
Abstract Background: This case was a twin pregnancy with a complete hydatidiform mole (CHM) and a co-existing fetus. Gestational trophoblastic neoplasia (GTN) and ovarian venous thrombosis (OVT) were diagnosed during the postpartum period. Case: A 25-year-old pregnant woman, gravid 2, para1-0-0-1 presented with vaginal bleeding. Ultrasonography showed multi-cystic placenta separated from a normal placenta and a living fetus. The patient had a vaginal delivery at 31+5 weeks of gestation. Placental histology described a CHM and negative p57(kip2) immunohistochemistry. Post-molar GTN was diagnosed after one month of delivery. Low-risk GTN was diagnosed with OVT. Clinical symptoms subsided after administrating of single-agent methotrexate and an anticoagulant and without complication during one year follow-up. Conclusion: CHM with a co-existing fetus needs imaging, prenatal genetics, and pathological plus p57(kip2) immunohistochemistry for diagnosis.
Thai Journal of Obstetrics and Gynaecology

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