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Clinical Characteristics and Risk Factors Associated with Chlamydia trachomatis Infection in Women Presenting At "Da Nang Hospital For Women and Children" |
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| รหัสดีโอไอ | |
| Creator | Kong Chi Pham |
| Title | Clinical Characteristics and Risk Factors Associated with Chlamydia trachomatis Infection in Women Presenting At "Da Nang Hospital For Women and Children" |
| Contributor | Nhat Minh Huynh, Chi Yen Ha Le, Viet Quoc Dao, Vinh Dinh Tran |
| Publisher | PIMDEE Co., Ltd. |
| Publication Year | 2567 |
| Journal Title | Thai Journal of Obstetrics and Gynaecology |
| Journal Vol. | 32 |
| Journal No. | 3 |
| Page no. | 178-185 |
| Keyword | Chlamydia trachomatis, ELISA, risk factors, characteristics, women |
| URL Website | https://tci-thaijo.org/index.php/tjog/index |
| Website title | www.tci-thaijo.org |
| ISSN | 2673-0871 |
| Abstract | Objectives: To investigate clinical characteristics and risk factors associated with Chlamydia trachomatis infection in women examined at Da Nang Hospital for Women and Children.Methods: This was a cross-sectional study of 600 women undergoing examinations at Da Nang Hospital for Women and Children from October 2018 to June 2019. All women were clinically examined and diagnosed with C. trachomatis infection by Enzyme-linked Immunosorbent Assay (ELISA) to determine the presence of serum IgM and IgG antibodies.Results: Chlamydia trachomatis (C. trachomatis) infection rate was 26.0%, of which 70.5% had positive IgG antibodies and 41.6% had positive IgM antibodies, whereas 12.1% had both IgM and IgG antibodies. The majority of patients (49.3%) reported at least three clinical symptoms. The most prevalent clinical and testing manifestations were abnormal vaginal discharge (88.5%), vaginitis (75.0%), cervicitis (65.4%), and Candida co-infection (14.7%). Risk factors associated with C. trachomatis infection included manual laborer (OR = 2.1, 95% CI 1.4 - 3.2, p = 0.0004), first sexual intercourse age < 18 years (OR = 1.9, 95%CI 1.2 - 2.7, p = 0.0023), pelvic pain (OR = 2.1, 95%CI 1.4 - 3.4, p = 0.0007), vaginitis (OR = 2.0, 95%CI 1.2 - 3.2, p = 0.0076), and cervicitis (OR = 2.2, 95% CI 1, 5 - 3.3, p = 0.0001).Conclusion: C. trachomatis infection accounts for a high percentage of women aged 18 or older who had experienced sexual intercourse presenting at Da Nang Hospital for Women and Children. Following the investigation of the risk factors, clinicians should pay particular attention to high-risk patients (manual laborer, first sexual intercourse age < 18 years, pelvic pain, vaginitis, cervitis) to enhance sensitivity to disease screening and facilitate timely detection and diagnosis. |
