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Rate of Large for Gestational Age Newborn Between Gestational Diabetes Mellitus followed-up by One-hour Postprandial Plasma Glucose and Two-hour Postprandial Plasma Glucose |
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| รหัสดีโอไอ | |
| Creator | Parichat Meeprasert |
| Title | Rate of Large for Gestational Age Newborn Between Gestational Diabetes Mellitus followed-up by One-hour Postprandial Plasma Glucose and Two-hour Postprandial Plasma Glucose |
| Contributor | Sirida Pittyanont |
| Publisher | PIMDEE Co., Ltd. |
| Publication Year | 2566 |
| Journal Title | Thai Journal of Obstetrics and Gynaecology |
| Journal Vol. | 31 |
| Journal No. | 6 |
| Page no. | 421-429 |
| Keyword | LGA, GDM, 1-HrPPG, 2-HrPPG |
| URL Website | https://tci-thaijo.org/index.php/tjog/index |
| Website title | www.tci-thaijo.org |
| ISSN | 2673-0871 |
| Abstract | Objectives: To compare the rate of large for gestational age (LGA) newborns, adverse perinatal, and obstetrical outcomes in gestational diabetes mellitus (GDM) followed-up by one-hour postprandial glucose (1-HrPPG) and two-hour postprandial glucose (2-HrPPG), and to study the risk factors increasing the rate of LGA newborns.Materials and Methods: In this retrospective cohort study, Thai singleton pregnancies with GDM diagnosed by using the Carpenter and Coustan criteria who were regularly followed-up and delivered a live birth after 28 weeks of gestation at Prapokklao Hospital between October 2017 to July 2022 were enrolled. The participants were classified into two groups based on the follow-up method. The data were collected from the medical records and analyzed by SPSS version 26.0.Results: Four hundred and seventy-eight participants were included and divided into two groups of 239 participants each. There were no differences in the baseline characteristics. In the obstetrical outcomes, metformin was used more (16.3% vs 4.2%, p < 0.001) in the 1-HrPPG group, but the others were not different. For the neonatal outcomes, the mean birthweight was higher in the 1-HrPPG group (3180.8 ? 460.6 vs 3098.0 ? 434.9 grams, p = 0.044), but the rate of LGA was not different (20.5% vs 20.1%, p = 0.909). After the logistic regression analysis, the excessive gestational weight gain doubled the risk of LGA. Conclusion: The rate of LGA newborns in GDM who were followed-up by 1-HrPPG or 2-HrPPG was not different, and the appropriate gestational weight gain could reduce the rate of LGA. |
