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Changes of Ovarian Reserve after Hysterectomy for Non-oncologic Conditions in Reproductive-aged Women: A prospective study |
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| รหัสดีโอไอ | |
| Creator | Natcha Silpaibulpanich |
| Title | Changes of Ovarian Reserve after Hysterectomy for Non-oncologic Conditions in Reproductive-aged Women: A prospective study |
| Contributor | Pruttaporn Maneerat |
| Publisher | PIMDEE Co., Ltd. |
| Publication Year | 2566 |
| Journal Title | Thai Journal of Obstetrics and Gynaecology |
| Journal Vol. | 31 |
| Journal No. | 5 |
| Page no. | 341-349 |
| Keyword | ovarian reserve, anti-mullerian hormone, ovarian volume, antral follicle count, hysterectomy |
| URL Website | https://tci-thaijo.org/index.php/tjog/index |
| Website title | www.tci-thaijo.org |
| ISSN | 2673-0871 |
| Abstract | Objectives: To assess the impact of hysterectomy on the ovarian reserve markers in reproductive-aged women.Materials and Methods: This prospective cohort study was conducted from May 2021 to April 2022. Reproductive-aged women who underwent hysterectomy without ovarian surgery due to benign conditions at Rajavithi Hospital were recruited. Ovarian reserve markers were compared between the date before surgery and 12 weeks following hysterectomy by measurement of serum anti-M?llerian hormone (AMH), antral follicle count (AFC) and ovarian volume (OV).Results: Fifty-five reproductive-aged women were enrolled. Different proportion (DP) between serum AMH at preoperative and 12 weeks postoperative was decreased after hysterectomy (DP 22.5%, p = 0.001). The antral follicle count (AFC) and ovarian volume (OV) were also decreased (DP 33.3%, p < 0.001, and 20.0%, p < 0.001, respectively). Nonetheless, surgical outcomes and menopausal symptoms were not different.Conclusion: Hysterectomy without ovarian surgery affects the ovarian reserve at 12 weeks post operation without significantly changing of menopausal symptoms. However, other long-term consequences from accelerated ovarian aging should be investigated. |
