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Use of Placental Pulsatility Index in High-Risk Pregnancy to Predict Fetal Growth Restriction |
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| รหัสดีโอไอ | |
| Creator | Natavadee Todumrong |
| Title | Use of Placental Pulsatility Index in High-Risk Pregnancy to Predict Fetal Growth Restriction |
| Contributor | Dhirapatara Charoenvidhya, Boonchai Uerpairojkit |
| Publisher | PIMDEE Co., Ltd. |
| Publication Year | 2565 |
| Journal Title | Thai Journal of Obstetrics and Gynaecology |
| Journal Vol. | 30 |
| Journal No. | 1 |
| Page no. | 68-75 |
| Keyword | placental pulsatility index, fetal growth restriction, adverse perinatal outcomes |
| URL Website | https://tci-thaijo.org/index.php/tjog/index |
| Website title | www.tci-thaijo.org |
| ISSN | 2673-0871 |
| Abstract | Objectives: The primary objective was to determine the predictive value of placental pulsatility index(PPI) in its ability to predict fetal growth restriction in singleton pregnant women at 16-24 weeksof gestation. The secondary objective was to evaluate PPI in predicting adverse perinataloutcomes and to compare the efficacy of PPI with conventional uterine artery pulsatility index(UtA PI) or umbilical artery pulsatility index (UA PI) alone.Materials and Methods: A prospective observational study enrolled singleton pregnant women at16- 24 weeks of gestation who were at high risk for fetal growth restriction and had prenatalcare at the King Chulalongkorn Memorial Hospital between February 12, 2018, and January28, 2019. UtA PI and UA PI were performed and calculated as PPI by transabdominalultrasonography. Pregnancy outcomes were recorded. The optimal cut-off for PPI was derivedfrom the receiver operating characteristic (ROC) curve to calculate the predictive values for fetalgrowth restriction.Results: A total of 446 pregnant women were enrolled into the study. Twenty-seven cases (6%)developed fetal growth restriction. The optimal cut-off for PPI at 16-24 weeks of gestation was1.38. The sensitivity, specificity, positive predictive value, and negative predictive value to predictfetal growth restriction were 66.7%, 78.8%, 16.8%, and 97.3%, respectively. The ROC curve ofthe PPI gave an area under the curve of 0.73 (95% CI,0.61-0.84).Conclusion: In second-trimester high-risk pregnancies, PPI had a comparable performance inpredicting FGR and adverse perinatal outcomes compared to UtA PI alone. |
