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The Effectiveness of Sublingual Misoprostol in Reducing Operative Blood Loss during Total Abdominal Hysterectomy: A randomized controlled trial |
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| รหัสดีโอไอ | |
| Creator | Tipsukon Harinsalai |
| Title | The Effectiveness of Sublingual Misoprostol in Reducing Operative Blood Loss during Total Abdominal Hysterectomy: A randomized controlled trial |
| Contributor | Manasicha Meckjarusnapa, Junyaporn Rattanakosol, Maleechat Sripipattanakul, Thumwadee Tangsiriwatthana |
| Publisher | PIMDEE Co., Ltd. |
| Publication Year | 2562 |
| Journal Title | Thai Journal of Obstetrics and Gynaecology |
| Journal Vol. | 27 |
| Journal No. | 4 |
| Page no. | 210-215 |
| Keyword | benign uterine diseases, misoprostrol |
| URL Website | https://tci-thaijo.org/index.php/tjog/index |
| Website title | www.tci-thaijo.org |
| ISSN | 2673-0871 |
| Abstract | Objectives: To study the effectiveness and safety of preoperative sublingual misoprostol administration in reducing of operative blood loss during total abdominal hysterectomy (TAH).Materials and Methods: Three hundred women with benign uterine diseases who were performed TAH at Khon Kaen Hospital from June 2017 to May 2018 were randomized into two groups: misoprostol group and placebo group. Intraoperative blood loss was analyzed.Results: Baseline characteristics were similar between groups. There was no statistically significant difference in intraoperative blood loss between misoprostol and placebo group [228 ml (126-389) vs 240 ml (126-387), p = 0.943]. There was no significant difference in hemoglobin difference, blood transfusion and hospital stay between groups.Conclusion: Misoprostol could not reduce intraoperative blood loss during total abdominal hysterectomy. |
