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Birth Weight/ Placental Weight Ratios: Does the association differ between early- and late-onset preeclampsia? |
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| รหัสดีโอไอ | |
| Creator | Podjanee Phadungkiatwattana |
| Title | Birth Weight/ Placental Weight Ratios: Does the association differ between early- and late-onset preeclampsia? |
| Contributor | Songphol Puttasiri |
| Publisher | PIMDEE Co., Ltd. |
| Publication Year | 2562 |
| Journal Title | Thai Journal of Obstetrics and Gynaecology |
| Journal Vol. | 27 |
| Journal No. | 3 |
| Page no. | 122-129 |
| Keyword | preeclampsia, placenta, birth weight, early onset, late onset |
| URL Website | https://tci-thaijo.org/index.php/tjog/index |
| Website title | www.tci-thaijo.org |
| ISSN | 2673-0871 |
| Abstract | Objectives: Early- and late-onset preeclampsia (PE) may differ in pathophysiology and this can bereflcted in differences in birth weight/placental weight (BW/Pl) ratios. Therefore, we comparedBW/Pl ratios of births with early- and those with late-onset PE.Materials and Methods: The retrospective descriptive study included all hospital-based singleton births of 24-43 weeks' gestation between January 2007 and December 2016. A total of 51,940 pregnant women were divided into three groups: early-onset PE, late-onset PE, and pregnant women without PE. Birth weight/placental weight were compared among 3 groups.Results: The mean (? standard deviation; SD) BW/Pl ratios were signifiantly different in early-onset PE and late-onset PE compared with the control group (3.91 ? 0.93 in early-onset PE, 4.85 ? 0.91 in late-onset PE and 5.17 ? 0.90 in the control group, p < 0.001). The factors signifiantly associated with BW/Pl ratios were race, infant gender, diabetes mellitus (DM), gestational age at delivery, early-onset PE, late-onset PE, small for gestational age (SGA) and large for gestational age (LGA). After adjustment for DM, gestational age at delivery, late-onset PE, SGA and LGA, the BW/Pl ratio was still associated signifiantly more with early-onset PE than with late-onset PE.Conclusion: The BW/Pl ratios of preeclamptic women differed between early- and late-onset PE, and that early-onset PE may be commonly associated with placental efficiency. This suggests that preeclampsia consists of several different processes manifesting as a single disease. |
