|
Prevalence of Hypothyroidism in Peri-/Post-MenopausalThai Women |
|---|---|
| รหัสดีโอไอ | |
| Creator | Kanokphon Butmarasri |
| Title | Prevalence of Hypothyroidism in Peri-/Post-MenopausalThai Women |
| Publisher | PIMDEE Co., Ltd. |
| Publication Year | 2560 |
| Journal Title | Thai Journal of Obstetrics and Gynaecology |
| Journal Vol. | 25 |
| Journal No. | 4 |
| Page no. | 275 |
| Keyword | menopausal women, hypothyroidism, Zulewski's clinical score, MENQOL |
| ISSN | 0857-6084 |
| Abstract | Objectives: This study aimed to determine the prevalence of hypothyroidism and its association withmenopausal symptoms and evaluated the diagnostic performance of Zulewski's clinical scorefor predicting hypothyroidism in peri-/post-menopausal Thai women.Materials and Methods: This hospital-based cross-sectional study was conducted between June2015 and April 2016 in Srinagarind Hospital, Khon Kaen, Thailand. We enrolled 305 peri-/postmenopausal women 45-65 years of age without previous history of thyroid diseases, radiationexposure at the neck, or concurrent use of lithium. The participants were interviewed by tworesearch assistants' vis-?-vis symptoms of menopause and hypothyroidism, current medicationsand menstrual characteristics. Blood samples were taken for TSH and FT4 levels. Mainoutcomes were prevalence of hypothyroidism, the Menopause-Specifi Quality of Life (MENQOL)score, and diagnostic performance of Zulewski's clinical score .Results: Mean age was 56 ? 4.7 years. The prevalence of hypothyroidism was 6.2% (95%CI 3.5%to 8.9%). The sensitivity of Zulewski's clinical score at the cutoff point ? 3 was 70%. Neitherthe MENQOL domain score nor the composite score was associated with hypothyroidism.Conclusion: The prevalence of hypothyroidism in peri-/post-menopausal Thai women is low. Thereis no association between MENQOL score and hypothyroidism. Zulewski's clinical score is nota good screening test for hypothyroidism in this group. |
