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Cesarean Section Rate in Oxytocin Infusion betweenContinuous Until Delivery and Discontinuation at ActivePhase of Labor: A randomized controlled study |
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| รหัสดีโอไอ | |
| Creator | Lalida Chookijkul, M.D. |
| Title | Cesarean Section Rate in Oxytocin Infusion betweenContinuous Until Delivery and Discontinuation at ActivePhase of Labor: A randomized controlled study |
| Publisher | PIMDEE Co., Ltd. |
| Publication Year | 2559 |
| Journal Title | Thai Journal of Obstetrics and Gynaecology |
| Journal Vol. | 24 |
| Journal No. | 2 |
| Page no. | 73-80 |
| Keyword | cesarean section rate, oxytocin, labor |
| ISSN | 0857-6084 |
| Abstract | Objective: To compare the cesarean section rate between discontinuing oxytocin infusion forlabor induction or augmentation when the active phase of labor is established and continuingoxytocin infusion until delivery.Materials and methods: This was a prospective randomized controlled trial of 340 pregnant womenwho underwent labor induction or augmentation at Bhumibol Adulyadej Hospital during February2014 to January 2015. Parturient were randomly and equally allocated into two groups. Thecontinued group received oxytocin infusion throughout all stages of labor. The discontinuedgroup received oxytocin infusion and early discontinued when the active phase of labor hadbegun. Intention to treat analysis was used in this study.Results: Three hundred and forty pregnant women were enrolled for the study. They wereassigned randomly into two groups, 170 patients for each group. Cesarean section rate incontinued and discontinued group were 31.8% and 27.7%, respectively (p = 0.40). The infusionof intravenous flid in CG group was stopped due to non-reassuring fetal heart rate pattern in15 women and total oxytocin doses used were signifiantly higher than that in DG group. InDG group, additional oxytocin was required due to poor uterine contraction. Duration of eachstage of labor, maternal complications and adverse neonatal outcomes were not signifiantlydifferent. There were only two cases of postpartum hemorrhage in discontinued group that wassuccessful managed by medical treatment.Conclusion: There was not sufficient evidence to support whether discontinuation or continuationof oxytocin in active phase of labor inflenced cesarean section rate. However, higher doses ofoxytocin used was found in continuation group. Future well-randomized design with enoughsample size is needed. |
