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ไอโซฟลาโวนจากถั่วเหลือง: ชีวเคมี กลไกการออกฤทธิ์ และความเกี่ยวข้องในการป้องกันมะเร็งเต้านม (Soy isoflavones: Biochemistry, mechanism of action and implication for breast cancer preventions) |
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| รหัสดีโอไอ | |
| Creator | Charin Thawornkuno |
| Title | ไอโซฟลาโวนจากถั่วเหลือง: ชีวเคมี กลไกการออกฤทธิ์ และความเกี่ยวข้องในการป้องกันมะเร็งเต้านม (Soy isoflavones: Biochemistry, mechanism of action and implication for breast cancer preventions) |
| Publisher | Genetics Society of Thailand |
| Publication Year | 2557 |
| Journal Title | Thai Journal of Genetics |
| Journal Vol. | 7 |
| Journal No. | 1 |
| Page no. | 7 |
| Keyword | isoflavone, estrogen, breast cancer |
| ISSN | 8578664 |
| Abstract | Cancer is a main problem of the current public health worldwide. In Thailand, this disease is in the highest rank of the cause of death since 1988, and the incidence rates of cancers are also rising. Cancer is a serious disease and can be fatal. Causes of cancer are diverse and complex. Several factors increase cancer risk such as diets, infections, radioactive exposures and environmental pollutants. It is currently accepted that consumptions some diet and certain eating habits can reduce the risk of cancer. Therefore, cancer preventive compounds from foods have been of great interest. Especially in 1990, when participants at a workshop supported by the National Cancer Institute proposed the possibility of isoflavones (polyphenolic non-steroidal found mostly in soy) in the prevention of several types of cancers. Since, many studies have mentioned the possibility of using isoflavones in the prevention of cancer particularly in breast cancer. In this article, the biochemistry, mechanism of action and implications for breast cancer preventions of the isoflavones, which was isolated form soy, are reviewed. |
