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โครโมโซมวายกับการศึกษาวิวัฒนาการของมนุษย์ (Y chromosome and the study of human evolution) |
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| รหัสดีโอไอ | |
| Creator | 1. Wibhu Kutanan 2. Daoroong Kangwanpong |
| Title | โครโมโซมวายกับการศึกษาวิวัฒนาการของมนุษย์ (Y chromosome and the study of human evolution) |
| Publisher | Genetics Society of Thailand |
| Publication Year | 2557 |
| Journal Title | Thai Journal of Genetics |
| Journal Vol. | 7 |
| Journal No. | 2 |
| Page no. | in press |
| Keyword | โครโมโซมวาย, แฮโปลกรุ๊ป, เชื้อสาย, วิวัฒนาการของมนุษย์, เอเชียตะวันออก, Y chromosome, haplogroup, lineage, human evolution, East Asia |
| ISSN | 8578667 |
| Abstract | The human Y chromosome is exclusively paternally inherited and most of its DNA does not undergo recombination during meiosis, resulting in transmission of the whole chromosome from father to son. These special features make the Y chromosome an efficient tool for inferring human population history in paternal lineage. This review article described the Y chromosomal structure, pattern of polymorphisms and factors that affect polymorphisms. Moreover, methods for studying Y chromosome haplogroup, like designation and classification for investigating paternal lineage, are reviewed. Information of the Y chromosomal haplogroup distributions support the Out-of-Africa theory and can be used to predict the migration history of the current human species into East Asia. The present genetic structure of East Asian populations is also reviewed. Finally, we discussed the possibility of developing the study of the Y chromosome for unraveling the complex history of modern human populations |