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ความผันแปรของดีเอ็นเอไมโทคอนเดรียในประชากรชาวเขมร จังหวัดสุรินทร์ ประเทศไทย |
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| รหัสดีโอไอ | |
| Creator | 1. พิชชาภา บุญโสดา 2. ศุภรัตน์ ศรีทะวงษ์ 3. สุปราณี ศรีกู่กา 4. วิภู กุตะนันท์ |
| Title | ความผันแปรของดีเอ็นเอไมโทคอนเดรียในประชากรชาวเขมร จังหวัดสุรินทร์ ประเทศไทย |
| Publisher | Genetics Society of Thailand |
| Publication Year | 2556 |
| Journal Title | Thai Journal of Genetics |
| Journal Vol. | 6 |
| Journal No. | 1 |
| Page no. | 40-48 |
| Keyword | mitochondrial DNA variation, the Khmer, genetic structure |
| ISSN | 8578664 |
| Abstract | The Khmer was recognized as the local inhabitant in the Northeast of Thailand. Khmer language was classified to Mon-Khmer sub-family, which is linguistically similar to languages of other local Mon-Khmer speaking groups in Thailand, e.g., Lawa, Palaung, Khamu and H'tin. Hitherto, genetic structure of the Khmer in Northeastern Thailand has not been reported yet. Thus, this study analyses mtDNA-HVR-I variation of the Khmer from Surin province in order to determine genetic diversity and genetic structure of the Khmer. Moreover, genetic affinity between the Khmer and other 31 compared populations (14 Mon-Khmer speaking populations and 17 Tai-Kadai speaking populations) was investigated. The results showed that haplotype diversity (0.9444 ? 0.0278) and nucleotide diversity (0.0127 ? 0.0068) of the Khmer were high. Genetic distance result indicated that the Khmer are most closely related to the H'tin, subgroup Pray, from Nan Province. MDS result revealed genetic differentiation among the Mon-Khmer speaking populations as well as between the Mon-Khmer speaking populations and the Tai-Kadai speaking populations. AMOVA and NJ tree analyses exhibited the influence of language to genetic structure of the Mon-Khmer speaking population, suggesting their shared common ancestors. |