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การแสดงออกของยีน TPT1 ในเซลล์เนื้อเยื่อในโพรงประสาทฟันมนุษย์เมื่อได้รับความร้อน (The Expression of TPT1 in Heat-treated Human Pulp Cells) |
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| รหัสดีโอไอ | |
| Creator | คณัสนันท์ จิรโชติกูล |
| Title | การแสดงออกของยีน TPT1 ในเซลล์เนื้อเยื่อในโพรงประสาทฟันมนุษย์เมื่อได้รับความร้อน (The Expression of TPT1 in Heat-treated Human Pulp Cells) |
| Publisher | Genetics Society of Thailand |
| Publication Year | 2556 |
| Journal Title | Thai Journal of Genetics |
| Journal Vol. | S.1 |
| Journal No. | S1 (Special Issue 1) |
| Page no. | 171-174 |
| Keyword | Translationally controlled tumor protein, TPT1, Human dental pulp cells |
| ISSN | 8578664 |
| Abstract | Translationally controlled tumor protein (TCTP) is usually described as a stress-related protein because of its highly regulated expression in stress conditions for protection against diverse cell stresses. In this study we investigated the expression of TPT1 (human TCTP's gene) in heat-treated human dental pulp cells (HDPCs). HDPCs were exposed to heat stress at 43 ?C for 45 min, and TPT1 expression was determined at various time points by quantitative real time polymerase chain reaction (qPCR). Our results show that expression of TPT1 in heat-treated human pulp cell is up regulated at 24 h after heat stress. However, the level of TPT1 expression in non-treated cell was not stable and gradually decreased over the time course of the study. These findings indicate that heat stress can modulate TPT1 expression in HDPCs |
