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Genetic abnormality of sperm in smoker |
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| รหัสดีโอไอ | |
| Creator | 1. Supattra Poeaim 2. Thanyaphat Promson 3. Apichart Kidsanapasit 4. Anurug Poeaim 5. Pornchai Laipasu |
| Title | Genetic abnormality of sperm in smoker |
| Publisher | Genetics Society of Thailand |
| Publication Year | 2551 |
| Journal Title | Thai Journal of Genetics |
| Journal Vol. | 1 |
| Journal No. | 1 |
| Page no. | 40 |
| Keyword | cigarette, chromosome aberration, fluorescence in situ hybridization (FISH) |
| ISSN | 8578664 |
| Abstract | There are many chemical compounds in cigarette. They can cause several diseases on smokers such as heart disease and lung cancer. Mutagen is also found in cigarette. In this experiment, sex chromosomes of 21 sperm?s donors from 18 to 26 years old were studied (seven non-smokers as the control group and fourteen smokers as the experiment group). X and Y chromosome were detected with DNA probes by fluorescence in situ hybridization (FISH). The results showed the significant difference in total sex chromosomes abnormality between experiment group and control group (13.07?10.194 and 5.29?1.890, respectively) (P<0.05) (mean?SD). Our study indicates that smoking cigarette causes numerical of sex chromosome aberration in sperm. |
