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Mechanisms of Essential Oils from Citronella (Cymbopogon winterianus Jowitt) Against Siamensis Subterranean Termite Workers (Coptotermes gestroi Wasmann) and Mice (Mus musculus L.) |
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| รหัสดีโอไอ | |
| Creator | 1. Parichart Upatoom 2. Suraphon Visetson |
| Title | Mechanisms of Essential Oils from Citronella (Cymbopogon winterianus Jowitt) Against Siamensis Subterranean Termite Workers (Coptotermes gestroi Wasmann) and Mice (Mus musculus L.) |
| Contributor | Department of Agriculture |
| Publisher | Department of Agriculture |
| Publication Year | 2560 |
| Journal Title | THAI AGRICULTURAL RESEARCH JOURNAL |
| Journal Vol. | 35 |
| Journal No. | 3 |
| Page no. | 270-295 |
| Keyword | Coptotermes gestroi Wasmann, Mus musculus L., Mechanisms, Citronella essential oils |
| URL Website | http://at.doa.go.th/journal |
| Website title | THAI AGRICULTURAL RESEARCH JOURNAL |
| ISSN | 1258389 |
| Abstract | This work aimed to evaluate the in vivo and in vitro toxicity of essential oils fromcitronella (Cymbopogon winterianus Jowitt) extract by tasting as contact and fumigationmethods against Siamensis termites (Coptotermes gestroi Wasmann). The in vivo and invitro acute oral toxicity were evaluated with mice (Mus musculus L.). The CRD with5 replicates for all experiments was designed. Probit analysis was used to elucidate LC50 fortermites and LD50 for mice. The in vivo LC50on the 14th day using the contact methodshowed ca. 0.54 mg/g and the fumigation method showed ca. 0.02 mg/g of essential oilsagainst termite workers. This is an indication that the in vivo fumigation method showedsignificantly more toxic against termites than the contact method by 27.02 fold. The invivo oral LD50of essential oils showed ca. 5.81 g/kg body weight for male and ca.17.42 g/kgbody weight for female at the 24th hour. The in vitro fumigation method also exhibited ca.<2-3 fold inhibited acetylcholinesterases (AChE) and glutathione-S-transferases (GSTs) andca. <1.5 fold inhibited esterases (ESTs) against termites compare to the untreated termites.While the in vitro in liver of mice exhibited ca. < 2 fold AChE and GSTs and ca. < 0.5 foldinhibited ESTs compare to the untreated mice control. But the contact method was likelynonsignificant in vitro enzymes activity compare to untreated mice control for allenzymes assays. |
