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Development of a high-performance liquid chromatographyfor analysis of corosolic acid in Lagerstroemia speciesand their hypoglycemic potentials |
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| รหัสดีโอไอ | |
| Creator | 1. Gorawit Yusakul 2. Paritad Saensom 3. Nattapol Mitsantia 4. Chattarika Pengdee 5. Waraporn Putalun |
| Title | Development of a high-performance liquid chromatographyfor analysis of corosolic acid in Lagerstroemia speciesand their hypoglycemic potentials |
| Publisher | Research and Development Office, Prince of Songkla University |
| Publication Year | 2563 |
| Journal Title | Songklanakarin Journal of Science and Technology |
| Journal Vol. | 42 |
| Journal No. | 2 |
| Page no. | 314-320 |
| Keyword | Lagerstroemia, corosolic acid, HPLC, ?-glucosidase inhibition, diabetes |
| URL Website | https://rdo.psu.ac.th/sjstweb/index.php |
| ISSN | 0125-3395 |
| Abstract | Worldwide people suffer from metabolic syndrome and its complications. For these conditions, functional foods arebecoming more important. We aimed to determine the amounts of corosolic acid in Lagerstroemia species and their ?glucosidase inhibitory potency. In addition, we developed a new source of corosolic acid using the plant tissue culture technique.The HPLC-UV method was reliable and applicable for corosolic acid determination of the Lagerstroemia species. Although thecorosolic acid standardized extract is usually prepared using L. speciosa, our results revealed that L. macrocarpa and L. loudoniicontained much higher amounts of corosolic acid. In addition, the established callus culture of L. speciosa produced corosolicacid with higher content than their parental L. speciosa mature leaves. The corosolic contents in these samples were also inagreement with ?-glucosidase inhibitory activity. Therefore, this method is worthy of antidiabetic standardization of Lagerstroemia derived materials. |
