Correlation Between Aortic Oxygen Saturation and Pulmonary Artery Size in Cyanotic Congenital Heart Disease With Decreased Pulmonary Blood Flow
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Creator Boonchu Sirichongkolthong
Title Correlation Between Aortic Oxygen Saturation and Pulmonary Artery Size in Cyanotic Congenital Heart Disease With Decreased Pulmonary Blood Flow
Contributor -
Publisher Faculty of Medicine Ramathibodi Hospital, Mahidol University
Publication Year 2561
Journal Title Ramathibodi Medical Journal
Journal Vol. 41
Journal No. 3
Page no. 021-029
Keyword Cyanotic congenital heart disease, Pulmonary artery branches, Oxygen saturation, McGoon ratio, Nakata index
URL Website https://www.tci-thaijo.org/index.php/ramajournal
Website title Ramathibodi Medical Journal
ISSN 0125-3611
Abstract Background: One of the indications for surgical planning in cyanotic congenital heart disease patients is the appropriate pulmonary artery size. Patient must be evaluated by an expert and in need of high-technology instruments. This is a limitation in situation with long waiting list of cardiac surgery.Objective: To find the correlations between McGoon ratio/Nakata index and aortic oxygen saturation in patients with cyanotic congenital heart disease with decreased pulmonary blood flow, and to identify the appropriate oxygen saturation for planning the surgical repair.Methods: The author reviewed angiograms of the patients who had cardiac catheterization at Thammasat Hospital from 2008 to 2017. The McGoon ratio and Nakata index were calculated and correlated to the aortic oxygen saturation by using the Pearson product moment correlation (r). The oxygen saturations that correspond to the surgical criteria values of McGoon ratio/Nakata index were estimated by using linear regression analysis.Results: A total of 100 cardiac catheterizations were performed in 82 patients. The correlation between McGoon ratio/Nakata index and aortic oxygen saturation were moderately correlated (r = 0.61 and r = 0.46 respectively). The patients were divided into 3 groups. Prediction of the oxygen saturations that corresponded to the surgical values of McGoon ratio and Nakata index were 73.47% (95% confidence interval [CI], 70.34 -76.62) and 75.87% (95% CI, 72.41 - 79.33) in Biventricular repair group, 76.23% (95% CI, 73.76 - 78.70) and 76.73% (95% CI, 74.24 - 79.23) in Univentricular repair without Glenn operation group, 82.29% (95% CI, 79.87 - 84.70) and 85.03% (95% CI, 81.57 - 88.49) in Univentricular repair with previous Glenn operation group, respectively.Conclusions: In this study, the lowest value of 95% CI of the predicted oxygen saturation in each group is selected to determine the patient who is not benefit to further investigation for total correction or Glenn/Fontan operation. For the Biventricular repair group, total correction should not be considered if oxygen saturation is less than 70%. In the Univentricular repair without Glenn operation group and the Univentricular repair previous Glenn operation group, the Glenn/Fontan operation should not be considered if oxygen saturation is less than 74% and 80%, respectively.
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