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Chemical constituents and cytotoxic effects of the essential oil fromthe root of Cyperus kyllingia Endl. |
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| รหัสดีโอไอ | |
| Creator | Noppawan Intecha |
| Title | Chemical constituents and cytotoxic effects of the essential oil fromthe root of Cyperus kyllingia Endl. |
| Contributor | Natcha Injan, Wanrudee Keawmesri, Manat Jaimasith,Chayanan Jitmanee, Sorachai Khamsan |
| Publisher | Division of research facilitation and dissemination Mahasarakham University |
| Publication Year | 2561 |
| Journal Title | Research and Knowledge |
| Journal Vol. | 4 |
| Journal No. | 2 |
| Page no. | 40-44 |
| Keyword | Cyperus kyllingia Endl., essential oil, anticancer activity, cytotoxicity, anti-TB activities |
| URL Website | rk.msu.ac.th |
| Website title | research and knowledge |
| ISSN | 2408-204X (printed), 2630-0400 (online) |
| Abstract | The chemical constituents of the essential oil from the root of Cyperus kyllingia Endl.were obtained from hydrodistillation and subsequently analyzed by a gas chromatography/massspectrometry (GC-MS) technique. Twenty-eight compounds were identified, accounting for 89.62%of the total oil that consisted mainly of oxygenated sesquiterpenes (50.21%) and sesquiterpenehydrocarbons (38.08%). ?-Cadinol (18.62%), caryophyllene oxide (12.18%), ?-muurolol (11.56%),Cyperene (10.15%), and ?-Cyperone (5.72%) were identified as the major components. The essentialoil showed significantl cytotoxicity against NCI-H187, and MCF-7 cell lines with IC50 values of 6.7and 13.3 ตg/mL, and was non-cytotoxic against Vero cells. Furthermore, the oil was active againstMycobacterium tuberculosis with a MIC value of 25.0 ตg/ mL.L3 |
