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Tyrosinase Inhibitory Efficiency and Antioxidant Activity of Gac Fruit (Momordica cochinchinensis Spreng.) Extract |
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| รหัสดีโอไอ | |
| Creator | Pornsinee Darapong |
| Title | Tyrosinase Inhibitory Efficiency and Antioxidant Activity of Gac Fruit (Momordica cochinchinensis Spreng.) Extract |
| Contributor | Sirichan Tachai, Jetchan Atthaisong, Nanthawan Jaikla, Buranee Rabiab, Rawinipa Srimoon |
| Publisher | Rajamangala University of Technology Tawan-Ok |
| Publication Year | 2566 |
| Journal Title | วารสารวิชาการและวิจัย มทร.พระนคร สาขาวิทยาศาสตร์และเทคโนโลยี |
| Journal Vol. | 17 |
| Journal No. | 2 |
| Page no. | 149-156 |
| Keyword | Antioxidant Activity, Gac fruit (Momordica cochinchinensis Spreng.), Tyrosinase |
| URL Website | https://ph02.tci-thaijo.org/index.php/RMUTP/index |
| Website title | วารสารวิชาการและวิจัย มทร.พระนคร สาขาวิทยาศาสตร์และเทคโนโลยี |
| ISSN | 2651-1096 |
| Abstract | This research evaluated the inhibitory efficiency of gac fruit (Momordica cochinchinensis Spreng.) extracts on tyrosinase and antioxidant activity. The results showed that ethanolic extract of aril had the highest tyrosinase inhibitory efficiency (80.57?0.50%), followed by peel extract and seed extract (p<0.05), respectively. The ethanolic extract of aril possessed the strongest tyrosinase inhibition of 1.28 fold compared with that of a standard inhibitor, kojic acid. Water extract of aril revealed the highest content of total phenolic compounds (1.291?0.011 mg GAE/g) and ethanolic extract of seed coat showed the strongest DPPH radical scavenging activity (63.18?0.34%). The inhibitory efficiency on tyrosinase associated with total phenolic content and antioxidant activity of the extract, especially in the ethanolic fraction. Our results can support the development of gac fruit extract for natural whitening products with further clinical study to confirm the efficiency and safety of the extract. It also enhances the economic value and reduces wastes of gac fruit, particularly peel and seed which were underutilized parts of fruit. |
