Reproductive Performance Comparisons of Three Inbred Mice Strains (BALB/cMlac,C57BL/6Mlac and DBA/2Mlac) at National Laboratory Animal Center, Mahidol University,Thailand
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Creator Pornrattana Chumanee;Apisit Laosantisuk;Wanson Keawmanee;Kanchana Kengkoom;Thanaporn Pinpart
Title Reproductive Performance Comparisons of Three Inbred Mice Strains (BALB/cMlac,C57BL/6Mlac and DBA/2Mlac) at National Laboratory Animal Center, Mahidol University,Thailand
Publisher คณะสิ่งแวดล้อมและทรัพยากรศาสตร์
Publication Year 2557
Journal Title วารสารการพัฒนางานประจำสู่งานวิจัย
Journal Vol. 1
Journal No. 1
Page no. 1
Keyword Mice;Inbred strains;Reproductive performance;NLAC-MU
ISSN ISSN2392-568X
Abstract Reproductive performance consisting of mean litter size, number of pups that wean (wean: born ratio)and mean reproductive index of three inbred mice strains, which are BALB/cMlac, C57BL/6Mlac andDBA/2Mlac, were investigated to provide some basic information on the breeding and maintaining of a foundation colony. These strains are designated as specific pathogen free animals (SPF) by the NationalLaboratory Animal Center, Mahidol University (NLAC-MU), the organization in which they were housedunder the maximum barrier system. The data from twenty generations of each strain were analyzed by t-test and non-parametric test. The mean litter size (born) values were 4.6?1, 6.2?1.4 and 4.3?1.0, and the wean:born ratios were 0.90?0.1, 0.81?0.2 and 0.83?0.2 for BALB/cMlac, C57BL/6Mlac andDBA/2Mlac, respectively. Furthermore, their mean reproductive indexes were 1.03, 0.94 and 0.71,respectively. Comparison results of the three inbred strains suggested that the reproductive performance of BALB/cMlac is better than that of C57BL/6Mlac and DBA/2Mlac.
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