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Controlling of Blood Pressure after Spinal Anesthesia for Cesarean Section with Different Techniques of Ephedrine Administration |
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| รหัสดีโอไอ | |
| Creator | Dujduen Sreeramart |
| Title | Controlling of Blood Pressure after Spinal Anesthesia for Cesarean Section with Different Techniques of Ephedrine Administration |
| Publisher | Faculty of Medicine,Srinakharinwirot University |
| Publication Year | 2548 |
| Journal Title | Journal of Medicine and Health Sciences |
| Journal Vol. | 12 |
| Journal No. | 2 |
| Page no. | 70-75 |
| Keyword | Spinal Anesthesia, hypotension, cesarean section, ephedrine |
| ISSN | 0859-3323 |
| Abstract | Spinal anesthesia (SA) is an acceptable anesthe ic technique for cesarean section (CS). The mostommon complication found in SA for obstetric patients is hypotension in varying severity. Ephedrine is useds the first line drug to prevent and correct hypotension during cesarean deliveries under SA because it does notecrease uterine blood flow. The objective of this study w s to compare the effect of ephedrine on controllingof blood pressure after SA for cesarean deliveries when given in a continuous infusion or intermittent bolusesmanner. A retrospective study was performed in 200 uncomplicated pregnancies scheduled for cesarean sectionunder SA at HRH Princess Maha Chakri Sirindhorn Medical Center from February 2004 March 2005.The patients were divided into 2 groups as Continuous group and Intermittent group. In Continuous group,the patients received a mixture of ephedrine 15-30 mg in isotonic saline solution after entering OR.In Intermittent group, the patients were given intermittent ephedrine injections when blood pressure fell below20% of their baseline values after SA. The parameters recorded were NIBP readings before delivery, theamount of ephedrine given, blood loss and fluid replacement. Patient's demographic data were similar amongtwo groups. The severity of hypotension in Continuous group was lesser than Intermittent group at 5, 10, 15, 20and 25 minutes (p = 0.023, 0.001, 0.000, 0.000, 0.001 respectively). The mean amount of ephedrine given wassignificantly greater in Continuous group (39.97 mg) than Intermittent group (19.12 mg) with P values of 0.000.The results suggested that continuous infusion of ephedrine before spinal anesthesia decreasing the severityof hypotension in cesarean section before delivery. |
