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Annexins:Ca2+ -Aependent memberanebinding proteins |
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| รหัสดีโอไอ | |
| Creator | Punnee Nusuetrong |
| Title | Annexins:Ca2+ -Aependent memberanebinding proteins |
| Publisher | Faculty of Medicine,Srinakharinwirot University |
| Publication Year | 2539 |
| Journal Title | Journal of Medicine and Health Sciences |
| Journal Vol. | 3 |
| Journal No. | 2 |
| Page no. | 95-99 |
| Keyword | Annexins |
| ISSN | 0859-3299 |
| Abstract | The annexins are a family of Ca2+ -dependdent phospholipid binding proteins. Each annexin, molecular weight 32000-39000,is composed of 4-6 homologous amphiphilic ?-helices, It acts by binding to the annionic phospholipid surface in elevation of Ca2+ concentration then organizes into trimers, hexamers, and higher aggregates; and ultimately forms an extended hexagonal array around the target protein (s) . The resultant inhibits phospholipid binding proteins such as inhibition phosphokinase (PKC) and phospholipase(PLasese) in activated CIฏ conductance and in other reaction : anticoagulant, hormone and neurotransmitter excytosis. |
