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Quality of life of in patients with heart failure with reduced ejection fraction |
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| รหัสดีโอไอ | |
| Creator | Voratima silavanich |
| Title | Quality of life of in patients with heart failure with reduced ejection fraction |
| Contributor | Unchalee Permsuwan |
| Publisher | Faculty of Pharmaceutical Sciences KKU MSU UBU |
| Publication Year | 2566 |
| Journal Title | Isan Journal of Pharmaceutical Sciences |
| Journal Vol. | 19 |
| Journal No. | 1 |
| Page no. | 15-31 |
| Keyword | health utility, chronic heart failure, EQ-5D |
| URL Website | https://tci-thaijo.org/index.php/IJPS |
| Website title | Isan Journal of Pharmaceutical Sciences, IJPS |
| ISSN | 19050852 |
| Abstract | This study aimed to measure the utility by using EuroQOL five-dimensional questionnaire (EQ-5D) and to examine the factors that affected the utility of patients withheart failure with reduced ejection fraction (HFrEF) . Method: This was a cross-sectional study. The data were collected from patients with HFrEF who were followed up at the outpatient department of Maharaj Nakorn Chiang Mai Hospital from 1st July to 31st December 2015. The EQ-5D-5L questionnaire consisted of two parts, the first part consisted of five health dimensions and the second part was a health status (Visual Analog Scale, VAS). Data were analyzed using descriptive statistics. Chi-square was performed to assess relationship between utility score and patient characteristics. Results: A total of 180 CHF patients were included. Mean age was 63.1?11.7 years; 61.1% were male. The mean scores of EQ-5D and visual analog scale (VAS) were 0.88 ? 0.10 and 78.29 ?11.97, respectively. About 50% of the total samples reported that they had no problem with mobility and pain/discomfort. Approximately 60% of the total samples reported no problem with doing usual activities and no problem with anxiety/depression. Almost all samples (95.6%) reported that they had no problem with self-care. It was found that advanced age, number of comorbidities (> 4 diseases), and average number of drug dosages per day (> 6 drugs) were influential factors affecting utility scores (p-value=0.005, p-value =0.012, and p-value =0.007, respectively). The significant factors affecting the VAS score included the educational level, length of time diagnosed with heart failure and recent admission from acute decompensated heart failure, which resulted in significantly lower VAS score (p-value=0.019, p-value=0.040 and p-value= 0.040, respectively). Conclusions: Patients with chronic heart failure in this study had a relatively good quality of life. However, factors that may contribute to a decrease in quality of life include increasing age, number of comorbidities, and number of medications. The significant factors should be monitored to increase the quality of life of HFrEF patients. |
