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Fruits Anti-Cancer Drugs Interaction Treatment |
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| รหัสดีโอไอ | |
| Creator | Surachet Lamkam |
| Title | Fruits Anti-Cancer Drugs Interaction Treatment |
| Contributor | Trai Tarnpanich |
| Publisher | Faculty of Pharmaceutical Sciences KKU MSU UBU |
| Publication Year | 2565 |
| Journal Title | Isan Journal of Pharmaceutical Sciences |
| Journal Vol. | 18 |
| Journal No. | 2 |
| Page no. | 1-13 |
| Keyword | Fruits, anti-cancer medications, Drug interaction, Cytochrome P450, P-glycoprotein |
| URL Website | https://tci-thaijo.org/index.php/IJPS |
| Website title | Isan Journal of Pharmaceutical Sciences, IJPS |
| ISSN | 19050852 |
| Abstract | Fruits are one kind of food which has been widely consumed. However, some fruits have reported altering the Cytochrome P450 enzyme and P-glycoprotein (P-gp). Fruit-drug interaction can occur when taken together. The list of fruits that have been reported to change the action of the enzymes and P-gp includes Grapefruit, Star fruit, Pineapple, and Pomelo. Thus, it might change cancer drug levels, affecting efficacy and adverse effect of treatment. Most data of fruit-drug interaction come from in vivo studies. Data of human clinical study is limited. However, the available data can be applied to monitoring adverse drug reactions of anti-cancer medications, pharmaceutical care in cancer patients, and providing information about consuming fruits safely in patients undergoing systemic medicines for cancers. |
