Utilization of Anti-Secretory Drugs for Stress Ulcer Prophylaxis in General Internal Medicine Wards
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Creator Areerut Leelathanalerk
Title Utilization of Anti-Secretory Drugs for Stress Ulcer Prophylaxis in General Internal Medicine Wards
Contributor Suratchada Chanasopon, Terdkiad Thiminkul, Narin Tiangboon
Publisher Faculty of Pharmaceutical Sciences KKU MSU UBU
Publication Year 2563
Journal Title Isan Journal ofPharmaceutical Sciences
Journal Vol. 16
Journal No. 2
Page no. 1-10
Keyword anti-secretory drugs, stress ulcer prophylaxis, internal medicine patient, proton pump inhibitors
URL Website https://tci-thaijo.org/index.php/IJPS
Website title Isan Journal ofPharmaceutical Sciences, IJPS
ISSN 19050852
Abstract Recent studies have shown that stress ulcer prophylaxis (SUP) is overutilized in inpatient medicine wards. Objective: To evaluate the utilization of antisecretory-drugs for SUP in general internal medicine services during hospital stay or at hospital discharge. Materials and Method: This study was a retrospective chart review of adult internal medicine patients admitted in hospital over a 1-year period. The number of patients receiving antisecretory drugs for SUP with the indications suggested by the American Society of Health-System Pharmacists (ASHP) guidelines were assessed. Results: Of the 200 patients who met inclusion criteria, 97 (48.5%) patients were prescribed antisecretory-drugs for SUP appropriately based on the guideline. A total of 103 patients received antisecretory-drugs without any indication. Of these, 52 patients (50.5%) continued antisecretory-drugs upon discharge. Conclusion: SUP was utilized inappropriately in patients admitted in general internal medicine wards. Moreover, antisecretory-drugs were frequently continued upon discharge without the indication. The overutilization of these medications may contribute increased risks of significant side effects and increased healthcare costs.
Faculty of Pharmaceutical Sciences, Khon Kaen University

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