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Phytochemical screening, total phenolic content and antioxidant capacities of selected blood tonic formula from vientiane province, Lao PDR |
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| รหัสดีโอไอ | |
| Creator | Souphaphone Sorsavanh |
| Title | Phytochemical screening, total phenolic content and antioxidant capacities of selected blood tonic formula from vientiane province, Lao PDR |
| Contributor | Wirat Ruengsitagoon |
| Publisher | Faculty of Pharmaceutical Sciences KKU MSU UBU |
| Publication Year | 2562 |
| Journal Title | Isan Journal of Pharmaceutical Sciences |
| Journal Vol. | 15 |
| Journal No. | 1 |
| Page no. | 181-194 |
| Keyword | Lao PDR, Antioxidant, Total Phenolic, Phytochemical screening, Blood tonic formula, Lao PDR, Antioxidant, Total Phenolic, Phytochemical screening, Blood tonic formula |
| URL Website | https://tci-thaijo.org/index.php/IJPS |
| Website title | Isan Journal ofPharmaceutical Sciences; IJPS |
| ISSN | 19050852 |
| Abstract | Lao People's Democratic Republic or Lao PDR is still a plenty source of medicinal plants used in traditional medicine for treating or preventing the illness as well as health maintenances. Objectives: The aims of this work were to investigate and compare the phytochemical screening, total phenolic content and antioxidant activities of blood tonic formula from Vientiane province, Lao PDR. Methods: The blood tonic formula and each herb that consisted of Knema globularia (Myristicaceae), K. furfuracea (Myristicaceae), Endosamara racemosa (Fabaceae) and Dendrophthoe pentandra (Loranthaceae) to determine phytochemical screening test. Then, prepared the water extracts by boiling to imitate real use and ethanol extracts by maceration. The crude extracts were determined total phenolic contents and antioxidant activities using DPPH ABTS FRAP and ORAC assays. Results: In vitro phytochemical screening for all plants showed positive results for flavonoids, terpenoids, steroids and tannins. The ethanol extract of E. racemosa displayed the highest total phenolic content (273.02 mg GAE/ g extract) and also exhibited the highest antioxidant activity with IC50 values of 26.80 ?g/ml (DPPH assay), 49.43 ?g/ml (ABTS assay) and 297.14 mg trolox equivalent/g extract (FRAP assay), respectively. Ethanol extract of D. pentandra showed the highest ORAC antioxidant activity (3385.77 ?M trolox equivalent/ g extract). This blood tonic formula and its individual herbs showed the relatively high antioxidant activity but lower than E. racemosa extract. Conclusion: The results of this study support the ethnomedicinal uses of the selected formula. The selected medicinal plants especially E. racemosa are potential sources of antioxidants. |
