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Adverse drug events identification using trigger tools in hospitalized patients |
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| รหัสดีโอไอ | |
| Creator | Vittanee Getupook |
| Title | Adverse drug events identification using trigger tools in hospitalized patients |
| Contributor | Kanokkoj Budnampet, Attaya Plangsanguan, Rujira Sopakorn |
| Publisher | Faculty of Pharmaceutical Sciences KKU MSU UBU |
| Publication Year | 2559 |
| Journal Title | Isan Journal of Pharmaceutical Sciences |
| Journal Vol. | 12 |
| Journal No. | 3 |
| Page no. | 16-23 |
| Keyword | Adverse drug events, Trigger Tools |
| URL Website | https://tci-thaijo.org/index.php/IJPS |
| Website title | Isan Journal ofPharmaceutical Sciences, IJPS |
| ISSN | 19050852 |
| Abstract | The aims of the present study were to identify and describe adverse drug events by trigger tools. Data were collected from retrospective record review of 561 patient charts which had 1 or more trigger tools and admissions longer than 48 hours during January to June 2014. The 4 trigger tools investigated in this study were calcium polystyrene sulphonate (Kalimate?), chlorpheniramine maleate injection (CPM injection), vitamin K injection (Konakion?) and naloxone injection (Narcan?). The particular adverse drug events which occurred during the admissions were counted and identified. The results showed that Kalimate? and vitamin K injection were prescribed most often (36.6% and 35.8% respectively) followed by CPM injection (27.5%). No naloxone injection was prescribed during the study time. The combined positive predictive value (PPV) of all trigger tools was 9.9% as follows Kalimate? 16.15% PPV, CPM injection 12.79% PPV, and vitamin K injection 1.34% PPV. This study indicated that KCl injection and KCl elixir were the causes of hyperkalemia (K 5.5 - 7.7 mEq/L) leading to Kalimate? prescription. Antibiotics were the most common cause of hypersensitivity leading to CPM injection prescription (81.8%). Most hypersensitivity reactions were skin rash, particularly maculo-papular rash (50%). Warfarin was the cause of high INR levels (INR 7-10) leading to vitamin K injection prescription. Trigger tools may be a useful method to identify adverse drug events in a short time continually using targeted chart review to find incidence of adverse drug events to improve patient safety. |
