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Assessment of pharmaceutical care outcomes on the patients with chronic obstructive pulmonary disease attending community hospital in Thailand |
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| รหัสดีโอไอ | |
| Creator | Piyawan Kuwalairat |
| Title | Assessment of pharmaceutical care outcomes on the patients with chronic obstructive pulmonary disease attending community hospital in Thailand |
| Contributor | Poradee Mayases, Anu Thongdang |
| Publisher | Faculty of Pharmaceutical Sciences KKU MSU UBU |
| Publication Year | 2557 |
| Journal Title | Isan Journal ofPharmaceutical Sciences |
| Journal Vol. | 10 |
| Journal No. | 1 |
| Page no. | 80-92 |
| Keyword | Chronic obstructive pulmonary disease (COPD), Pharmaceutical care, Pharmacist |
| URL Website | https://tci-thaijo.org/index.php/IJPS |
| Website title | Isan Journal ofPharmaceutical Sciences, IJPS |
| ISSN | 19050852 |
| Abstract | Background : Chronic obstructive pulmonary disease (COPD) is health problem that increase in prevalence. As COPD is not fully reversible airway obstructive disease, the multidisciplinary team intervene follow GOLD guideline to achieve clinical outcome. Paknum-Chumphon hospital initiated an ambulatory COPD clinic run by physicians, pharmacists and nurses. Its pharmaceutical care impacts remained unassessed. Objective: This study aimed to evaluate the impacts of pharmaceutical care on patients' medication outcomes (inhaler techniques scores and drug related problems, DRPs) and clinical outcomes (PEFR, FEV1, COPD Assessment Test (CAT) scores and dyspnea scores). Subjects and Methods: The pretest-posttest one-group study was carried out in outpatients of Paknum-Chumphon Hospital from October 1, 2010 to December 31, 2011. Adult patients diagnosed with definite COPD were included in the study and those attending the COPD clinic less than six months afterwards were excluded. All patients were assessed by two pharmacists and nurses for medication and clinical outcomes before receiving pharmacists' interventions that embraced advice on COPD, medicine, inhaler techniques and lifestyle modification. At 6 months they were reassessed for the same COPD outcomes. Relevant data were gathered and analyzed using a paired t-test and ?2 test with the significance level determined at ?= 0.05. Results: A total of 80 patients were assessed and 12 were excluded. The majority of patients were male (67.5%) with the mean age of 65.2 years (SD=13.3). The average COPD duration was 6.3 years (SD=2.8). After the counseling interventions, patients' inhaler technique scores significantly increased from 83.0% to 93.4% (p=0.001). A significant reduction in the number of DRPs was detected after the interventions (p=0.001). Most DRPs before the interventions were 'improper drug selection' (37.1%), but after that were 'failure to receive drugs' (8.1%). Patients' PEFR (55.8% vs 61.9%, p=0.001) and CAT scores (23.2 vs 15.9, p=0.001) were significantly improved. An insignificant improvement were found in FEV1 (60.4% vs 67.4%), targeted dyspnea score 0-1 (83.8% vs 95.0%) and combined assessment of COPD type A and B (52.5% vs 58.8%). Conclusions: Pharmaceutical care provided by pharmacist in the multidisciplinary COPD team for COPD patients could improve patients' inhaler techniques, reduce drug-related problems and enable them to achieve the desired therapeutic outcomes of COPD management.spectrometry. Results: The volatile oil contents of ginger rhizomes and capsules were in the range of 0.69 to 2.45 percent volume per weight. Gas chromatography identified 20 compounds in the volatile oil of fresh ginger rhizomes and 5 compounds in volatile oil of ginger capsules. The main component found in volatile oil of fresh ginger rhizomes and ginger capsules was zingiberene (11.9-39.5% of the area under the peaks). Mass spectrum technique and retention index based on the comparison with NIST MS library database provided consistent results in identifying compounds found in the ginger volatile oil. Conclusion: Retention index could be used to examine the compositions of volatile oil in the ginger capsules comparing to ginger rhizomes from the same sources. |
