Blood Glucose Level and Hematological Values in Diabetic Rats Received Leaf Extract from Clerodendrum disparifolium Blume.
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Creator Chusri Talubmook
Title Blood Glucose Level and Hematological Values in Diabetic Rats Received Leaf Extract from Clerodendrum disparifolium Blume.
Contributor Jatuporn Phaopongthai
Publisher Faculty of Pharmaceutical Sciences KKU MSU UBU
Publication Year 2553
Journal Title Isan Journal ofPharmaceutical Sciences
Journal Vol. 6
Journal No. 1
Page no. 77-84
Keyword Clerodendrum disparifolium Blume., Diabetic rats, Blood glucose level, Hematological values
URL Website https://tci-thaijo.org/index.php/IJPS
Website title Isan Journal ofPharmaceutical Sciences, IJPS
ISSN 19050852
Abstract This study aimed to investigate blood glucose level and hematological values in diabetic rats treatedwith the leaf extract from Clerodendrum disparifolium Blume. Rats were induced to be diabetes by giving asingle peritoneal injection of 65 mg/kg streptozotocin. The rats with the fasting blood glucose level above126 mg/dl were used as diabetic rats. The extract at a dose of 250 mg/kg was given orally and daily to the diabetic rats for 8 weeks. The blood glucose level of the treated rats was determined weekly. Thehematological values; packed cell volume, hemoglobin concentration, red blood cell count, and whiteblood cell count were measured at the end of the experiments. The results showed that the extract canrecover the diabetic state in the experimental animals in this study by lowering the blood glucose level andproduce the hematological value in diabetic rats closely to the normal controls.
Faculty of Pharmaceutical Sciences, Khon Kaen University

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