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The Effect of the Interventions on Basic Knowledge of and Skills of Health Care Workers in the Preparation of Cytotoxic Drugs at Sappasithiprasong Hospital, Ubon Ratchathani Province |
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| รหัสดีโอไอ | |
| Creator | Anun Chaikoolvatana |
| Title | The Effect of the Interventions on Basic Knowledge of and Skills of Health Care Workers in the Preparation of Cytotoxic Drugs at Sappasithiprasong Hospital, Ubon Ratchathani Province |
| Contributor | Jirana Anansushatgul, Wannaporn Wattanapong |
| Publisher | Faculty of Pharmaceutical Sciences KKU MSU UBU |
| Publication Year | 2553 |
| Journal Title | Isan Journal ofPharmaceutical Sciences |
| Journal Vol. | 6 |
| Journal No. | 1 |
| Page no. | 66-76 |
| Keyword | Cytotoxic drugs preparation, Interventions, Aseptic hand-washing, Vertical laminar air flow |
| URL Website | https://tci-thaijo.org/index.php/IJPS |
| Website title | Isan Journal ofPharmaceutical Sciences, IJPS |
| ISSN | 19050852 |
| Abstract | The study aimed to evaluate the effects of the interventions including; a lecture on cytotoxicpreparation and practice simulation on the basic knowledge of and skills in the preparation of cytotoxicdrugs before, immediately after, and one month after the interventions. The study was designed as a onegroup pre-/post-test type in which eight participants completed a pre-test of a measurement of basicknowledge of cytotoxic drugs as well as an assessment of skills involved in cytotoxic preparations. Thisassessment was developed based on a standard checklist of preparation skills from a range of differentguidelines and was subsequently implemented by a panel of assessors consisting of three clinicalpharmacists, 4 technicians, and 1 temporary staff working. The participants were then exposed to theinterventions containing of a lecture on cytotoxic preparation, practice simulation on the basic knowledgeof and skills in cytotoxic preparation, then the assessments were repeated. Results from these processeswere followed by immediate post-test. One month later, similar assessments of basic knowledge and skillswere also performed. Attitudes of the participants toward these processes were also evaluated. The resultswere reported using descriptive & statistical analyses in term of mean ? SD, frequencies, paired t-tests,and Wilcoxon. The results showed there was no significant differences between basic knowledge scores inpre- compared to immediate post-tests, and in immediate compared to 1 month post-tests (p = 0.070and 0.336 respectively). The overall results of the skills assessment in cytotoxic drugs preparationdemonstrated significant differences in scores including basic knowledge, cytotoxic drugs preparation skillsbetween the pre- and immediate post-tests, and between the scores in the immediate posttest and 1 Interventions on Basic Knowledge of and Skills of Health Care Workers in the Preparation of Cytotoxic Drugs month post-tests (p = 0.026 and 0.045 respectively). The immediate posttest scores were significantlyhigher in all aspects preparation skills compared to those of pre-test (p = 0.001, 0.021, and 0.017respectively). However, there were no significant differences between the immediate posttest and 1 monthpost-test scores in the 3 skills including; aseptic hand-washing, vertical laminar air flow hood, andhazardous drug vial preparation (p = 0.279, 0.593, and 0.086, respectively). Generally, the attitudes ofthe participants to the implementation of the intervention were favorable. Conclusively, the interventionimproved basic knowledge of and skills in the preparation of cytotoxic drugs and participants? attitudes tothe intervention were positively favorable. |
