Occurrence and Removal of Antibiotics in Hospital Wastewater Treatment Plants
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Creator 1. Panadda Kanmalai
2. Yanasinee Suma
3. Chongrak Polprasert
4. Numfon Eaktasang
Title Occurrence and Removal of Antibiotics in Hospital Wastewater Treatment Plants
Publisher Thai Society of Higher Education Institutes on Environment
Publication Year 2566
Journal Title EnvironmentAsia
Journal Vol. 16
Journal No. 2
Page no. 118-126
Keyword Antibiotic, Conventional activated sludge, Hospital wastewater, Wastewatertreatment system
URL Website http://www.tshe.org/ea/index.html
Website title EnvironmentAsia
ISSN 1906-1718
Abstract In hospitals, antibiotics are utilized to treat human infectious illnesses, where extraantibiotics are frequently discharged and left in hospital wastewater. However, investigatingantibiotic residues using conventional activated sludge wastewater treatment plants in hospitalshas still been very limited, especially in Thailand. This research studied the contaminationof antibiotics in the conventional activated sludge wastewater treatment plants from threehospitals: a first-level hospital (H1), a middle-level hospital (H2), and an advanced-levelhospital (H3). The antibiotics were focused on 3 groups: bata-lactams, quinolones, andtetracyclines, which included 7 types of antibiotics (amoxicillin, ampicillin, ciprofloxacin,norfloxacin, levofloxacin, ofloxacin, and doxycycline). Antibiotics were extracted by solid-phaseextraction and analyzed by liquid chromatography-mass spectrometry (LC-MS/MS).The results showed that amoxicillin had the highest concentrations of H2, H1, and H3 in theinfluent (18,434 ? 99, 11,541 ? 42 and 10,994 ? 56 ng/L, respectively). Furthermore, with7,990 ? 53, 5,879 ? 52 and 4,892 ? 63 ng/L of H2, H3, and H1, respectively, amoxicillin appeared to have the highest concentrations in the effluent. The removal efficiency was the highest for norfloxacin (94.78%) in H1, followed by doxycycline (93.99%) in H2. However, ampicillin had the lowest removal efficiency (19.02%) in H2. This finding from the research on antibiotic contamination in hospital wastewater reveal that the conventional activated sludge treatment system could not completely remove all antibiotics in the wastewater. Therefore, the advanced treatment technology should be investigated to increase the antibiotics removal efficiency.
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