Effects of Black ginger (Kaempferia parviflora) on thetesticular function in streptozotocin-induced diabeticmale rats
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Creator 1. Wirasak Fungfuang
2. Teerayuth Lert-Amornpat
3. Chan Maketon
Title Effects of Black ginger (Kaempferia parviflora) on thetesticular function in streptozotocin-induced diabeticmale rats
Publisher คณะสัตวแพทยศาสตร์ มหาวิทยาลัยเชียงใหม่
Publication Year 2559
Journal Title เชียงใหม่สัตวแพทยสาร
Journal Vol. 14
Journal No. 3
Page no. 95-107
Keyword Diabetes mellitus, Testes, Testosterone, Kaempferia parviflora
ISSN 1685-9502 (print) 2465-4605 (online)
Abstract The present study aimed to investigate the efficacy of Black ginger (Kaempferia parviflora; KP) on testicular function instreptozotocin (STZ)-induced diabetes rats (DM). Six-week-old male Wistar rats were used in this experiment. All rats wererandomly divided into six group; group 1: Normal group, group 2: DM (control), group 3: DM rats received gibencamide 5mg/kg, group 4-6: DM rats received KP 140, 280 and 420 mg/kg, respectively. DM was induced by intraperitoneal injection ofSTZ (60 mg/kg). All animals were treated for 6 weeks. Blood glucose, epididymal sperm parameter, testicular microstructureand testosterone level were evaluated. The result showed that KP treatment has no effect on blood glucose in DM rats. KPtreatment showed significantly increased sperm density, serum testosterone and ameliorates testicular structure in DM rats(p<0.05). The present study indicates that the aphrodisiac properties of KP could improve of sperm density, testosterone level and testicular function in STZ-induced diabetes rats
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