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Immunohistochemistry of the chondroitin sulfate epitope in various normal human tissues of fresh cadavers |
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| รหัสดีโอไอ | |
| Creator | 1. Opat Keerewatcharaporn 2. Siriwan Ongchai 3. Sikrai Loawatnapong 4. Lamaiporn Peerapapong 5. Peeraphan Pothacharoen 6. Sirinda Aungsuchawan |
| Title | Immunohistochemistry of the chondroitin sulfate epitope in various normal human tissues of fresh cadavers |
| Publisher | Faculty of Medicine |
| Publication Year | 2558 |
| Journal Title | Chiang Mai Medical Journal |
| Journal Vol. | 55 |
| Journal No. | 1 |
| Page no. | 1-7 |
| Keyword | chondroitin sulfate,glycosaminoglycans,Immunohistochemistry,WF6 epitope |
| ISSN | 0125-5983 |
| Abstract | Objective The purpose of this study was to reveal the expression trend of the WF6 epitope in various normal human tissues.Methods Ten types of tissue samples from the brain, adipose, skeletal muscle, tendon, liver, cartilage, cardiac muscle, lung, nerve, and, skin were used in this study. They were obtained from fi ve fresh cadavers aged 20-70 years and stained with H and E for their general morphology. In addition, expression of the WF6 epitope was examined using immuno localization.Results The results demonstrated that WF6 epitope expression in the ten tissues can be categorized into three levels, with the highest being found in the brain, skeletal muscle, cartilage, cardiac muscle and skin tissues. A moderate level was found in the adipose, liver, lung and nerve tissues, and the lowest level was found in the tendon tissue.Conclusion The WF6 epitope was expressed at different levels in all of the various normal tissues. This re fl ects the important role of this biomolecule for all cells, which may be bene fi cial for further study in pathological tissues. |
