Biochemical Composition and Bioactive Properties ofChlorella minutissima(Chm1) as a Potential Source of Chemical CompoundsforNutritional Feed Supplementand Disease Control in Aquaculture
รหัสดีโอไอ
Creator Eldrin DLR. Arguelles
Title Biochemical Composition and Bioactive Properties ofChlorella minutissima(Chm1) as a Potential Source of Chemical CompoundsforNutritional Feed Supplementand Disease Control in Aquaculture
Publisher King Mongkut's Institute of Technology Ladkrabang
Publication Year 2564
Journal Title Current Applied Science and Technology
Journal Vol. 21
Journal No. 1
Page no. 65-77
Keyword Antibacterial activity, antioxidantactivity, bioactive compounds, bacterial fish pathogen, Chlorella, microalgae, proximateanalysis
URL Website https://www.tci-thaijo.org/index.php/cast
Website title https://www.tci-thaijo.org/index.php
ISSN 2586-9396
Abstract Microalgae contain high levels of proteins, lipids,carbohydratesand other bioactive metabolites with direct relevance to aquaculture. This investigation was done to assess the bioactive propertiesanddescribe the neutraceuticaland pharmacological benefitsof a green microalga, Chlorella minutissima(Chm1). The alga has a total phenolic content of 30.94ฑ0.06 mg GAEg-1. Relative antioxidant efficiency showed that C. minutissimaexerted potent ABTS scavenging activity and high ability of reducing copper ions in a concentration-dependent manner with IC50valuesof 48.13?g GAEml-1and 13.90 ?g GAEml-1, respectively.Evaluation of antibacterial activities using microtiter plate dilution assay revealed that C. minutissimashowed strong activity against Aeromonas hydrophila with a minimum inhibitory concentration (MIC) of 125 ?g ml-1. The algal extract is alsoeffective against Vibrio cholerae, Vibrio parahaemolyticusand Staphylococcus aureusin each casewith MIC value of 250 ?g ml-1. Also, C. minutissimaextract was able to inhibitthe growth of Pseudomonas fluorescenswithMIC value of 500 ?g ml-1. Proximate composition of the dried microalga showed that C. minutissimaconsistsofhigh protein, ash and crude fat content with values of 42.61ฑ0.11%, 17.79ฑ0.04% and 11.70 ฑ0.01%,respectively. The results show that C. minutissimais an excellent candidate organism as a potential source of chemical compounds important for feed formulation and disease control in aquaculture.
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