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Formulation of herbal concealer containing fennel seed oil and lavender oil with anti-Propionibacterium acnes activity |
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| รหัสดีโอไอ | |
| Creator | Aurasorn Saraphanchotiwitthaya |
| Title | Formulation of herbal concealer containing fennel seed oil and lavender oil with anti-Propionibacterium acnes activity |
| Contributor | Wanaree Rukpracha, Pattana Sripalakit |
| Publisher | Asia-Pacific Journal of Science and Technology |
| Publication Year | 2567 |
| Journal Title | Asia-Pacific Journal of Science and Technology |
| Journal Vol. | 29 |
| Journal No. | 1 |
| Page no. | 7 |
| Keyword | Anti-acne concealer, Emulsion, Fennel seed oil, Formulation, Lavender oil, Stability testing |
| URL Website | https://so01.tci-thaijo.org/index.php/APST |
| Website title | https://so01.tci-thaijo.org/index.php/APST/article/view/254796 |
| ISSN | 2539-6293 |
| Abstract | Acne is one of the most prevalent dermatologic diseases worldwide. Several substances derived from the herb are currently utilized to treat acne. Interestingly, incorporating essential oils with anti-Propionibacterium (P) acnes activity into concealer may help manage acne as well as conceal skin flaws. The study aimed to formulate a concealer with anti-acne properties, using Thai herbal oil with anti-P. acnes activities, and determine the formulation's stability. The anti-microbial activity against P. acnes DMST 14916 of fennel seed oil (FSO) and lavender oil (LO), and mixtures of the two was evaluated using agar disc diffusion and microbroth dilution assays. Concealers containing oils that have effective anti-P. acnes activity were formulated and tested for stability under the determined storage conditions. The result showed that FSO and LO in the ratio of 50:50 exhibited the highest inhibition against P. acnes of 23.39ยฑ0.48 mm of the inhibition zone with a minimum inhibitory concentration value of 1.56 mg/L. A silicone-based concealer incorporating 0.2% of these blended oils was formulated. F7 provided good texture, spreadability and coverage properties among the seven formulations, and had a pleasant odour. This formulation was biologically, chemically, and physically stable under the determined stability testing storage. In conclusion, a silicone-based anti-acne concealer containing blended oils of FSO and LO (50:50) was successfully developed. This formulation (F7) may be utilized both to manage acne and conceal skin imperfections problems using the benefits of herbal preparations. |