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Establishment of reference intervals in biochemistry parameters from check-up records: AMS Medical Laboratory, Khon Kaen |
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| รหัสดีโอไอ | |
| Creator | Patcharee Jearanaikoon |
| Title | Establishment of reference intervals in biochemistry parameters from check-up records: AMS Medical Laboratory, Khon Kaen |
| Contributor | Patutong Chatchawal, Molin Wongwattanakul, Chatladda Thubthimngam, Chanin Yotsakullert |
| Publisher | Asia-Pacific Journal of Science and Technology |
| Publication Year | 2567 |
| Journal Title | Asia-Pacific Journal of Science and Technology |
| Journal Vol. | 29 |
| Journal No. | 1 |
| Page no. | 9 |
| Keyword | Reference interval, Biochemistry parameters, Khon Kaen, Age-affected reference interval, Aging society, Health promotion |
| URL Website | https://so01.tci-thaijo.org/index.php/APST |
| Website title | https://so01.tci-thaijo.org/index.php/APST/article/view/271232 |
| ISSN | 2539-6293 |
| Abstract | Reference intervals are used as a decision-making tool to distinguish healthy individuals from those with specific diseases. Due to the variations among laboratories, reagent manufacturers, ethnic backgrounds, gender, and age, laboratories were recommended to develop their own reference intervals. Moreover, under the international standard requirement, laboratories should review their own reference intervals periodically. This study aims to re-establish the reference intervals of 10 common biochemistry parameters including glucose, BUN, creatinine, total cholesterol, triglyceride, HDL-c, LDL-c, AST, ALT, and ALP. The study was based on the retrospective dataset retrieved from AMS Medical Laboratory, Khon Kaen University. The 1,543 records of each parameter were tested for variation among age and gender subgroups prior to calculation of the reference intervals. The data showed no variation against male and female subgroups, while slightly increased values were observed in the aging subgroup. Age-dependent reference intervals were established in 6 parameters with >95% acceptance, while ranges of lipid profiles still rely on the NCEP guidelines. The findings emphasized the importance of age-affected reference intervals for populations. Moreover, the flexibility of new reference intervals was appropriate for an aging society and may motivate greater healthcare awareness. |
