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Potential Role of Electrochemotherapy as Anticancer Treatment for Cutaneous and Subcutaneous Lesions |
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| รหัสดีโอไอ | |
| Creator | 1. Anna Zygogianni 2. George Kyrgias; John Scarlatos; Michael Koukourakis; Kyriakos Souliotis; John Kouvaris; Nikolaos Kelekis; Vassilis Kouloulias |
| Title | Potential Role of Electrochemotherapy as Anticancer Treatment for Cutaneous and Subcutaneous Lesions |
| Publisher | APJCP |
| Publication Year | 2559 |
| Journal Title | Asian Pacific Journal of Cancer Prevention |
| Journal Vol. | 17 |
| Journal No. | 8 |
| Page no. | 3753-3757 |
| Keyword | Electrochemotherapy ; efficacy ; cost-effectiveness analysis ; skin lesions |
| Abstract | Background: The aim of this study was to investigate whether electrochemotherapy is a clinically and cost- effective treatment option against skin tumors. Materials and Methods: We performed an analysis of the current literature based on database searches in PubMed/MEDLINE and we included articles till July 2012. Terms used for the search were electrochemotherapy๊, skin cancer๊, recurrence๊, and cutaneous and subcutaneous tumors๊. Only papers published in English were included. In addition, we performed an analysis of the cost effectiveness of the method. Results: The combination of physics and chemistry is the foundation for electrochemotherapy and its ef cacy, independent of the tumor histology. Clinical data showed that ECT is well tolerated and can be used in dif cult cases without other available treatment options. The analysis also showed that the treatment is feasible and cost-effective. Conclusions: Electrochemotherapy is a clinically ef cient safe and cost-effective treatment and clinicians should not hesitate to use it as alternative therapeutic modality or as palliative treatment. |
