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Association Between Meconium-stained Amniotic Fluid and Obstetric Perineal Wound Infection |
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| รหัสดีโอไอ | |
| Creator | Sirarat Ittipuripat |
| Title | Association Between Meconium-stained Amniotic Fluid and Obstetric Perineal Wound Infection |
| Contributor | Surasith Chaithongwongwatthana |
| Publisher | PIMDEE Co., Ltd. |
| Publication Year | 2568 |
| Journal Title | Thai Journal of Obstetrics and Gynaecology |
| Journal Vol. | 33 |
| Journal No. | 5 |
| Page no. | 390-398 |
| Keyword | infected episiotomy wound, meconium-stained amniotic fluid, obstetric perineal wound infection |
| URL Website | https://tci-thaijo.org/index.php/tjog/index |
| Website title | www.tci-thaijo.org |
| ISSN | 2673-0871 |
| Abstract | Objectives: Meconium-stained amniotic fluid (MSAF) has been associated with higher rates of surgical site infection. The present study aimed to investigate the association between MSAF and obstetric perineal wound infections, and other puerperal infections, to inform the preventive strategies. Materials and Methods: This retrospective cohort study reviewed medical records of women delivered at King Chulalongkorn Memorial Hospital from January 1, 2018 to December 31, 2020. Women who underwent vaginal delivery with episiotomy or had an obstetric perineal wound and were followed up at 6 weeks postpartum were included. The cohort comprised of pregnancies complicated by MSAF (n = 366) and those without MSAF (n = 1,464). The primary outcomes were the incidence of infected episiotomy wounds and wound dehiscence. Percentages and 95% confidence intervals (CI) were calculated for categorical variables and odds ratios (OR) with 95% CI were used for comparisons between groups. Results: A total of 1,830 patients were included, with a mean age of 29.5 years. The rate of infected episiotomy wound in the MSAF group (3.55%, 95% CI 1.89 to 6.07) did not significantly differ from that of the non-MSAF group (3.55%, 95% CI 2.65 to 4.66), yielding an OR of 1.00 (95% CI 0.54 to 1.86). Similarly, there was no significant difference in the rate of wound dehiscence, chorioamnionitis, and other puerperal infections between the groups. Conclusion: Our findings suggested that MSAF was not associated with an increased risk of obstetric perineal wound infection. Therefore, antibiotic prophylaxis to prevent such infections in women with MSAF may not be necessary. |
