Efficacy of 10% Lidocaine Spray for Relief Postpartum Perineal Wound Pain: A randomized controlled trial
รหัสดีโอไอ
Creator Uthaiwan Suwannapab
Title Efficacy of 10% Lidocaine Spray for Relief Postpartum Perineal Wound Pain: A randomized controlled trial
Contributor Saranya Chatpongtada
Publisher PIMDEE Co., Ltd.
Publication Year 2568
Journal Title Thai Journal of Obstetrics and Gynaecology
Journal Vol. 33
Journal No. 2
Page no. 126-135
Keyword perineal wound pain, pain control, lidocaine spray, postpartum
URL Website https://tci-thaijo.org/index.php/tjog/index
Website title www.tci-thaijo.org
ISSN 2673-0871
Abstract Objectives: To evaluate the effectiveness of 10% lidocaine spray for reducing postpartum perineal wound pain.Materials and Methods: Postpartum women who had spontaneous delivery with first- or second-degree perineal tears and received wound repair were randomly assigned into two groups. The intervention group received a 10% lidocaine spray, and the control group received a sterile water spray applied to the perineum every 6 hours until reaching 48 hours after delivery. The primary outcome was perineal wound pain using a 10-cm visual analog scale (VAS) 48 hours after delivery. Student t-test and generalized estimating equation (GEE) population-averaged model were used. Results: Seventy-two women were randomly divided into two groups, 36 women in each group. Perineal wound pain at 24 and 48 hours in the lidocaine spray group was significantly lower than the control group (2.3 ? 0.2 vs 3.5 ? 0.2; mean difference 1.2; 95% confidence interval (CI) 0.4 to 2.0; p = 0.003) and (1.7 ? 0.2 vs 3.1 ? 1.6; mean difference 1.4; 95%CI 0.7 to 2.1; p < 0.001), respectively. Pain intensity in the lidocaine spray group was also significantly lower than the control group (mean difference = -0.4; 95%CI -0.6 to -0.1; p = 0.004). No serious adverse effects were observed in this study. Conclusion: The 10% lidocaine spray was effective in the reduction of perineal wound pain after spontaneous delivery.
Thai Journal of Obstetrics and Gynaecology

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