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Lidocaine Prilocaine Cream versus Intracervical Injection for Pain Relief during Loop Electrosurgical Excision Procedure |
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| รหัสดีโอไอ | |
| Creator | Kotchanipha Phaethayanan |
| Title | Lidocaine Prilocaine Cream versus Intracervical Injection for Pain Relief during Loop Electrosurgical Excision Procedure |
| Contributor | Chinnawat Srinil |
| Publisher | PIMDEE Co., Ltd. |
| Publication Year | 2566 |
| Journal Title | Thai Journal of Obstetrics and Gynaecology |
| Journal Vol. | 31 |
| Journal No. | 1 |
| Page no. | 40-47 |
| Keyword | loop electrosurgical excision procedure, LEEP, lidocaine prilocaine cream, intracervical injection, visual analog scale |
| URL Website | https://tci-thaijo.org/index.php/tjog/index |
| Website title | www.tci-thaijo.org |
| ISSN | 2673-0871 |
| Abstract | Objectives: To compare the effectiveness between lidocaine prilocaine cream versus intracervical injection for pain relief during loop electrosurgical excision procedure (LEEP).Materials and Methods: Sixty women who underwent LEEP at Khon Kaen Hospital were enrolled in a single, blinded, non-inferiority randomized controlled trial. The participants were randomly allocated into two groups; group 1 received lidocaine prilocaine cream applied to the cervix (n = 30), and group 2 intracervical injection (n = 30) before performing LEEP. The pain score was measured at speculum placement, during anesthetization, during the procedure, immediately after, and 30 min after the procedure, using the 10-cm visual analogue scale (VAS). In addition, we recorded adverse events and additional analgesia.Results: Baseline characteristics were similar between groups. The mean pain score during LEEP among groups was not significantly different between intracervical injections (control group) (5.53 ? 0.46, 95% confidence interval (CI) 4.60-6.47 vs. 4.59 ? 0.44, 95%CI 3.68-5.50, p = 0.145). The mean pain score during anesthetization with lidocaine prilocaine cream (intervention group) was significantly lower than with the intracervical injection (1.20 ? 0.29, 95%CI 0.60-1.80 vs. 3.62 ? 0.48, 95%CI 2.64-4.60, p < 0.001). No serious adverse events occurred.Conclusion: Lidocaine prilocaine cream was not significantly different intracervical injection for pain relief during LEEP and provided better pain relief during anesthetization (than in the control group) without serious adverse events. |
