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Defining risk thresholds: Appropriate body mass index cut-off for hypertension in Thai Cohort Study |
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| รหัสดีโอไอ | |
| Creator | Nipa Sakolchai |
| Title | Defining risk thresholds: Appropriate body mass index cut-off for hypertension in Thai Cohort Study |
| Contributor | Prasutr Thawornchaisit , Ferdinandus de Looze, Christopher M Reid , Sam-ang Seubsman and Adrian Sleigh |
| Publisher | Nakhon Pathom Rajabhat University |
| Publication Year | 2562 |
| Journal Title | Interdisciplinary Research Review |
| Journal Vol. | 14 |
| Journal No. | 4 |
| Page no. | 25 |
| Keyword | hypertension, body mass index, cut-o point for hypertension, Thailand |
| URL Website | http://apps.npru.ac.th |
| Website title | สถาบันวิจัยและพัฒนา มหาวิทยาลัยราชภัฏนครปฐม |
| ISSN | 2697-522X |
| Abstract | Body mass index (BMI) is used to predict the risk of hypertension in some Western countries. But to date the appropriateBMI cut-o for hypertension among Thais remains unresolved. This study aims to determine the proper BMI cut-o for risk ofhypertension in Thailand.Health-risk factors and their e ects on incidence of hypertension were evaluated prospectively in the national Thai CohortStudy from 2005 to 2013. All derived from 40548 initially normotensive Sukhothai Thammathirat Open University studentsreturning mail-based questionnaire surveys in both 2005 and 2013. Adjusted relative risks of association between baseline BMIand 8-year incidence of hypertension were calculated after controlling for a wide array of confounding factors. A smooth modelwith a linear fit of associations between BMI and hypertension risk was compared to a non-linear model using cubic splines.In Thailand, the 8-year incidence of hypertension was 5.1% (men 7.1%, women 3.6%). Hypertension was strongly associatedwith ageing and high BMI. Non-linear modelling showed the best fit with a significant upwards inflection pointing to the riskthreshold occurred in the third BMI category of 20.75 (aRR = 1.89, 95% CI 1.54-2.32) compared to a reference BMI of 20.00kg/m2.The health risk transition Thailand has led to a rising prevalence of hypertension which is an important risk factor for manychronic diseases. A BMI cut-o point of 21 kg/m2, two points lower than the current 23 kg/m2, would be appropriate fordefining the threshold of hypertension risk in Thai adults. Lowering BMI cut-o for risk of hypertension will encourage peopleto have more awareness of their health. Our results support population level interventions design to increase exercise anddecrease overweight and obesity in Thailand. |
