Distribution of Genetic Variants of the Rabies Virus in the Russian Federation
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Creator Larisa Gnezdilova, Vita Laga, Saida Marzanova, Sergey Pozyabin, Elena Yarygina
Title Distribution of Genetic Variants of the Rabies Virus in the Russian Federation
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Publisher TuEngr Group
Publication Year 2565
Journal Title International Transaction Journal of Engineering, Management, & Applied Sciences & Technologies
Journal Vol. 13
Journal No. 12
Page no. 13A12A: 1-8
Keyword Rabies, Epizootological analysis, Molecular genetic analysis, Sequencing.
URL Website http://TuEngr.com/Vol13-12.html
Website title ITJEMAST V13(12) 2022 @ TuEngr.com
ISSN 2228-9860
Abstract Rabies is a social, economically significant disease. According to the World Health Organization, rabies is one of the five economically significant diseases. Domestic and wild animals of all kinds and humans are susceptible to rabies. The disease is registered in various countries of the globe, including Russia. In this article, using the example of the rabies virus, the difference between the quality and availability of epidemiological and molecular genetic data is shown. Using the nucleotide sequences of the rabies virus, the sequences of the N gene (nucleoprotein) and the G gene (glycoprotein) were constructed. Analysis of phylogenetic trees built on the basis of rabies virus sequences showed the presence of homogeneous clusters from a number of regions of the country, with the simultaneous presence of heterogeneous clusters. This fact suggests that in a number of regions of the Russian Federation there are conditions for the isolated circulation of genetic variants of the rabies virus.
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