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Factors Related to Club Cell Protein 16 (CC16) and Quality of Life in Northern Thailand |
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| รหัสดีโอไอ | |
| Creator | 1. Sawitree Nangola 2. Sakesun Thongtip 3. Somphot Saoin 4. Chiraphat Kloypan 5. Sittichai Pimonsree 6. Kraichat Tantrakarnapa |
| Title | Factors Related to Club Cell Protein 16 (CC16) and Quality of Life in Northern Thailand |
| Publisher | Thai Society of Higher Education Institutes on Environment |
| Publication Year | 2566 |
| Journal Title | EnvironmentAsia |
| Journal Vol. | 16 |
| Journal No. | 1 |
| Page no. | 169-183 |
| Keyword | Club cell protein16 (CC16), Air pollution, PM10, PM2.5, Quality of life (QoL) |
| URL Website | http://www.tshe.org/ea/index.html |
| Website title | EnvironmentAsia |
| ISSN | 1906-1722 |
| Abstract | Exposure to poor air quality can cause adverse health effects, especially club cell protein16 (CC16) as potential marker for a lung injury, and a reduced quality of life (QoL). Thisstudy aimed to evaluate factors related to CC16 and QoL among people living near the airquality monitoring stations in Northern Thailand. A cross-sectional study was conducted.A total of 240 individuals were recruited. Data was collected using structured 36-itemshort-form survey (SF-36) questionnaires. Air quality was measured using air qualitymonitoring stations by the Pollution Control Department (PCD), Thailand. Diseases andrelated health problems were defined using the International Classification of DiseasesICD-10) by the Information and Communication Technology Center, Thailand. Venousblood was collected and analyzed for serum CC16 by medical laboratory technicians.The daily PM10 and PM2.5 concentrations were significantly positively associated withI00-I99 and J00-J99.8. The mean ? SD of serum CC16 levels in participants under60 years old was 5.33 ? 4.24 ng/ml, which was significantly lower than 10.01 ? 6.91 ng/mlin participants 60 years and older (p value < 0.001). The serum CC16 level wassignificantly associated with physical health (PH), mental health (MH), and overallQoL. Multiple linear regression analysis showed that an increase in serum CC16level was associated with a decrease in overall QoL after adjusting for confoundingvariables. Concerned agencies should provide policymakers and health promotioninterventions for reducing pollution exposure and self-protective behaviors toprevent airway inflammatory responses, chronic respiratory diseases, and poor QoL. |
