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Comparative evaluation of Tc-99m DTPA and Tc-99m MAG3 post-transplant renal scintigraphy for predicting one-year renal function in kidney transplant recipients |
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| รหัสดีโอไอ | |
| Creator | Bandit Thinkhamrop |
| Title | Comparative evaluation of Tc-99m DTPA and Tc-99m MAG3 post-transplant renal scintigraphy for predicting one-year renal function in kidney transplant recipients |
| Contributor | Daris Theerakulpisut, Sirirat Anutrakulchai |
| Publisher | Asia-Pacific Journal of Science and Technology |
| Publication Year | 2565 |
| Journal Title | Asia-Pacific Journal of Science and Technology |
| Journal Vol. | 27 |
| Journal No. | 6 |
| Page no. | 8 |
| Keyword | Graft function, Graft outcome, Kidney transplantation, Radionuclide imaging, Renal scintigraphy |
| URL Website | https://www.tci-thaijo.org/index.php/APST |
| Website title | https://so01.tci-thaijo.org/index.php/APST/article/view/262628 |
| ISSN | 2539-6293 |
| Abstract | This study aimed to compare renal scintigraphy (RS) using Tc-99m DTPA and Tc-99m MAG3 for predicting suboptimal renal function 1-year after kidney transplantation (KT) and correlation with renal function. This retrospective study included patients who underwent Tc-99m DTPA and Tc-99m MAG3 RS within 30 days after KT. Patients with serum creatinine at 1-year of ?1.5 mg/dL and >1.5 mg/dL were classified as having good and suboptimal renal function, respectively. Area under receiver operating characteristic curve (AUCROC) was used to determine predictiveness of RS parameters in predicting suboptimal renal function. Spearman's correlation was used to determine correlation between RS parameters and estimated glomerular filtration rate (eGFR). Of 227 patients, mean age was 42?10.5 years, 61.2% were males, 94.3% underwent deceased-donor KT. 56 patients (24.7%) had suboptimal 1-year renal function. The highest AUCROC is 0.71 for effective renal plasma flow rate from Tc-99m MAG3 RS but no significant differences in AUCROC between parameters from Tc-99m DTPA RS vs. Tc-99m MAG3 RS were found. Three parameters including time to peak, 20-min to peak ratio, and 20-min to 3-min, when obtained from Tc-99m MAG3 RS, had significant negative correlation with eGFR at 1-year (?: -0.18, -0.25, and -0.24, respectively) while those obtained from Tc-99m DTPA RS had no correlation. Tc-99m DTPA and Tc-99m MAG3 RS had no significant difference in predicting 1-year suboptimal post-KT renal function. However, time to peak, 20-min to peak ratio, 20-min to 3-min ratio were better correlated with eGFR when obtained from Tc-99m MAG3 RS. |
