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Antidiabetic, tyrosinase inhibitory, and free radical scavenging activitiesof the purified extracts from Morinda citrifolia unripe fruits |
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| รหัสดีโอไอ | |
| Creator | 1. Jintana Masoongnoen 2. Sompong Sansenya 3. Kongaphisith Tongpoolsomjit 4. Jarupa Viyoch 5. Kanokorn Wechakorn |
| Title | Antidiabetic, tyrosinase inhibitory, and free radical scavenging activitiesof the purified extracts from Morinda citrifolia unripe fruits |
| Publisher | Research and Development Office, Prince of Songkla University |
| Publication Year | 2565 |
| Journal Title | Songklanakarin Journal of Science an Technology (SJST) |
| Journal Vol. | 44 |
| Journal No. | 3 |
| Page no. | 735-743 |
| Keyword | Morinda citrifolia unripe fruit extract, tyrosinase inhibition, glucosidase inhibition, amylase inhibition, free radical scavenging |
| URL Website | https://rdo.psu.ac.th/sjst/index.php |
| ISSN | 0125-3395 |
| Abstract | The crude extracts from medicinal plants are increasingly important for bioactive activities. Several parts of Morindacitrifolia have been utilized in traditional medicine, such as diabetes, anticancer, and hypertension. Therefore, the purpose of thisresearch was to investigate the biological activities, e.g., antioxidant, antidiabetic, and tyrosinase inhibitory activity of the crudeextracts of Morinda citrifolia unripe fruits. The highest percent extraction was found in methanol. The purified methanoicfraction displayed the highest total phenolic content and was a potent tyrosinase inhibitor. The fraction of ethyl acetate exhibitedthe highest flavonoid content and DPPH free radical scavenging capacity. Furthermore, the ethyl acetate and methanol fractionswere investigated as potent ๏ก-glucosidase and ๏ก-amylase inhibitors. Additionally, the cytotoxicity test of the bioactive fractionswas explored in human keratinocyte cell lines. |
