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Effects of pomegranate rind (Punica granatum Linn.) and guava leafextract (Psidium guajava Linn.) for inhibition of multidrug resistantEscherichia coli recovered from diarrhoeal piglets |
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| รหัสดีโอไอ | |
| Creator | 1. Kridda Chukiatsiri 2. Kittiphong Tippaya 3. Ruttayaporn Ngasaman |
| Title | Effects of pomegranate rind (Punica granatum Linn.) and guava leafextract (Psidium guajava Linn.) for inhibition of multidrug resistantEscherichia coli recovered from diarrhoeal piglets |
| Publisher | Research and Development Office, Prince of Songkla University |
| Publication Year | 2564 |
| Journal Title | Songklanakarin Journal of Science and Technology (SJST) |
| Journal Vol. | 43 |
| Journal No. | 1 |
| Page no. | 45-49 |
| Keyword | E. coli, pomegranate rind, guava leaves, antimicrobial resistance, piglet |
| URL Website | https://rdo.psu.ac.th/sjstweb/index.php |
| ISSN | 0125-3395 |
| Abstract | The resistance of Escherichia coli to antimicrobial drugs is widespread in Thailand and globally. The antimicrobialproperties of some traditional plants have been studied as potential replacements of modern antibacterial agents. The objective ofthis study was to determine the antimicrobial resistance of E. coli isolated from diarrhoeal piglets and the efficacy ofpomegranate rind and guava leaf extract to inhibit the growth of E. coli. Fifty isolates of E. coli from piglets with diarrhea werecollected from swine farms in Chiang Mai province. The resistance to 11 antimicrobial drugs was tested using the broth microdilution method. All isolates were multidrug resistant. The most frequent were novobiocin, streptomycin, sulfamethoxazole,tetracyclin, and tiamulin (100 %). Followed by resistance to amoxicillin (98%), oxytetracyclin (96%), nalidixic acid (82%),gentamicin (56%), and colistin sulphate (46%). Pomegranate rind, guava leaf extract using the Soxhlet extraction method, and95% ethanol as solvent were tested for their ability to inhibit the growth of drug resistant E. coli using the agar dilution method.Pomegranate rind and guava leaf extract exhibited antibacterial activity against all E. coli isolates with an average minimuminhibitory concentration of 5.94 mg/mL and 9.44 mg/mL, respectively. The results demonstrate the possibility of using herbalextracts in the prevention and treatment of high level antimicrobial-resistant E. coli in pigs. |
