|
In vitro antioxidant potential of Mallotus repandus (Willd.) Muell. Argstem extract and its active constituent bergenin |
|---|---|
| รหัสดีโอไอ | |
| Creator | 1. Yollada Sriset 2. Waranya Chatuphonprasert 3. Kanokwan Jarukamjorn |
| Title | In vitro antioxidant potential of Mallotus repandus (Willd.) Muell. Argstem extract and its active constituent bergenin |
| Publisher | Research and Development Office, Prince of Songkla University |
| Publication Year | 2564 |
| Journal Title | Songklanakarin Journal of Science and Technology (SJST) |
| Journal Vol. | 43 |
| Journal No. | 1 |
| Page no. | 24-30 |
| Keyword | Mallotus repandus, bergenin, antioxidant activity |
| URL Website | https://rdo.psu.ac.th/sjstweb/index.php |
| ISSN | 0125-3395 |
| Abstract | Mallotus repandus (MR) is used in Thai traditional medicine recipes for anti-inflammation and adaptive homeostasis.Bergenin is the bioactive constituent in MR stem. This study evaluated the in vitro antioxidant activity of bergenin and themethanol, ethanol, and water extracts of MR stem prepared by maceration and Soxhlet extraction by assaying 2,2-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS?+), hydroxyl (?OH), superoxide (?O2), and nitric oxide (NO?)radical scavenging activities and ferric reducing antioxidant power. Bergenin had the highest ferric reducing power and all theMR extracts showed concentration-dependent ferric reducing power. Methanol and water extracts showed superior radicalscavenging activities compared to ethanol extract. The water and methanol Soxhlet extracts demonstrated the highest ABTS?+ and?OH radical scavenging activities, respectively, and the macerated water extract had the lowest ?O2 and NO?IC50 values.Therefore, MR stem and bergenin are promising natural candidates for developing antioxidant supplements. |
