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Development of combinative method using HPLC fingerprints andquantitative analysis for quality assessment of Chantaleela preparation |
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| รหัสดีโอไอ | |
| Creator | 1. Dujhathai Anekchai 2. Athip Sakunphueak |
| Title | Development of combinative method using HPLC fingerprints andquantitative analysis for quality assessment of Chantaleela preparation |
| Publisher | Research and Development Office, Prince of Songkla University |
| Publication Year | 2564 |
| Journal Title | Songklanakarin Journal of Science an Technology (SJST) |
| Journal Vol. | 43 |
| Journal No. | 6 |
| Page no. | 1556-1562 |
| Keyword | Chantaleela, HPLC fingerprint, quality control, traditional medicine, combinative herbal preparation |
| URL Website | https://rdo.psu.ac.th/sjst/index.php |
| ISSN | 0125-3395 |
| Abstract | Chantaleela (CTL) is a Thai traditional medicine composed of 8 medicinal herbs and borneol and used to treat fever.This study aimed to control the quality of CTL products by establishing a simple but comprehensive method using highperformance liquid chromatography (HPLC). HPLC fingerprints of CTL were constructed for assessing qualitative parametersfor identification and chemical profiling. This method is highly precise and accurate in quantifying the constituents of CTLidentifying markers including eurycomanone, loureirin A, imperatorin and atractylodin. The quality of commercial CTL productsin Thailand was assessed using this developed method. The chromatographic pattern was noticeably different from theestablished reference fingerprints. The substitution of Artemisia vulgaris for Artemisia annua was found in every commercialproduct. Moreover, the low content of marker compounds reflected poor quality of the commercial products. |
