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The fabric facial mask enhanced skin permeation of hydrophilicbioactive compounds in Aquilaria crassna leaf extract |
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| รหัสดีโอไอ | |
| Creator | 1. Eakkaluk Wongwad 2. Kornkanok Ingkaninan 3. Wudtichai Wisuitiprot 4. Neti Waranuch |
| Title | The fabric facial mask enhanced skin permeation of hydrophilicbioactive compounds in Aquilaria crassna leaf extract |
| Publisher | Research and Development Office, Prince of Songkla University |
| Publication Year | 2564 |
| Journal Title | Songklanakarin Journal of Science an Technology (SJST) |
| Journal Vol. | 43 |
| Journal No. | 5 |
| Page no. | 1335-1341 |
| Keyword | A. crassna leaf extract, cosmetics, partition coefficient, skin permeation, stability study |
| URL Website | https://rdo.psu.ac.th/sjst/index.php |
| ISSN | 0125-3395 |
| Abstract | The purpose of this study was to investigate the effects of a facial mask in enhancing skin absorption of iriflophenone3,5-C-?-D-diglucoside (1), iriflophenone 3-C-?-D-glucoside (2) and mangiferin (3). Partition coefficients (log Po/w) of 13 weredetermined. Facial essence containing Aquilaria crassna leaf extract was formulated and incorporated into a fabric facial mask.An in-vitro skin permeation of 13 from the formulation with and without the mask through human skin was evaluated usingFranz diffusion cells. Log Po/w of 13 were -1.03 ? 0.14, -0.54 ? 0.01 and 0.26 ? 0.01, respectively. The permeations of 13 fromthe formulation without fabric mask were only 0.26%, 0.58% and 0.61% of applied dose, respectively while those with the fabricmask were 0.79%, 1.08% and 0.70% of applied dose, respectively. In conclusion, the fabric mask enhances the skin permeationof the hydrophilic compounds 1, 2 more than that of compound 3, which is less hydrophilic. |
